SCHEMBL20143446

SCHEMBL20143446

CCc1ccc(Oc2ccc(CC)c(I)c2)cc1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 6/20 0.34
SLC6A4 P31645 5/20 0.34
KCNH2 Q12809 4/20 0.34
THRA P10827 2/20 0.33
THRB P10828 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
PCNA P12004 3/20 0.32
LMNA P02545 2/20 0.32
ABCB11 O95342 1/20 0.32
CYP1A2 P05177 1/20 0.32
PGR P06401 1/20 0.32
POLB P06746 1/20 0.32
CHRM2 P08172 1/20 0.32
HTR1A P08908 1/20 0.32
ADRA2A P08913 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
AR P10275 1/20 0.32
CYP2C9 P11712 1/20 0.32
GABRA1 P14867 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15746151 0.83 HTR2A (0.46) HTR2ASLC6A4KCNH2SMN1; SMN2LMNA
SCHEMBL10268647 0.81 TEAD4 (0.45) HTR2ASLC6A4KCNH2SMN1; SMN2LMNA
SCHEMBL15186252 0.80 LTA4H (0.50) SMN1; SMN2LMNAHPGD
SCHEMBL15186278 0.80 LTA4H (0.45) SMN1; SMN2LMNACYP1A2ARCYP2C9
SCHEMBL15186258 0.79 HTR2A (0.47) HTR2ASLC6A4KCNH2
SCHEMBL10825619 0.76 HPGD (0.48) SMN1; SMN2LMNAPOLBHPGDGFER
SCHEMBL1690285 0.75 HTT (0.46) POLBHPGDHSD17B10KMT2A
SCHEMBL14752089 0.75 PPARD (0.43) HTR2ASLC6A4KCNH2LMNAPPARG
SCHEMBL15702905 0.75 PGR (0.51) HTR2ASLC6A4KCNH2LMNAPGR
SCHEMBL13110336 0.73 NQO1 (0.52) LMNACYP1A2HPGDHSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9971202-B2 Alignment layer, liquid crystal display including the same, and method of manufacturing liquid crystal display SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-15 US disclosed