SCHEMBL157462

SCHEMBL157462

COC(=O)C=Cc1ccc(C(C)C)cc1C(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
KDM4E B2RXH2 5/20 0.48
MAPT P10636 3/20 0.48
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
TP53 P04637 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
CYP2C19 P33261 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TYR P14679 3/20 0.42
TTR P02766 1/20 0.42
APP P05067 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29435132 1.00 ALDH1A1 (0.48) ALDH1A1KDM4EMAPTKMT2AMEN1
SCHEMBL645927 1.00 ALDH1A1 (0.48) ALDH1A1KDM4EMAPTKMT2AMEN1
SCHEMBL647921 0.88 ALDH1A1 (0.48) ALDH1A1KDM4EMAPTKMT2AMEN1
SCHEMBL29520699 0.88 ALDH1A1 (0.48) ALDH1A1KDM4EMAPTKMT2AMEN1
SCHEMBL156609 0.88 ALDH1A1 (0.48) ALDH1A1KDM4EMAPTKMT2AMEN1
E-Methyl Cinnamate SCHEMBL28948986 0.88 KDM4E (0.51) KDM4EKMT2ATYRTTRAPP
E-Methyl Cinnamate SCHEMBL28810582 0.88 KDM4E (0.51) KDM4EKMT2ATYRTTRAPP
SCHEMBL25211344 0.87 CA12 (0.48) KDM4EMAPTTYRCA12CA1
SCHEMBL15514 0.84 TYR (0.50) MAPTTYRTTRCA12CA1
SCHEMBL648606 0.84 TYR (0.50) MAPTTYRTTRCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2169 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119015394-A Sulfur-containing compound preparation, and preparation method and application thereof 上海优斐斯生物科技有限公司 2024-11-26 CN claimed
US-20240374492-A1 A SUNSCREEN COMPOSITION COMPRISING AVOBENZONE AND A METHOD FOR PHOTOSTABILIZATION ISP INVESTMENTS LLC (US) 2024-11-14 US claimed
US-20240173235-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. 2024-05-30 US claimed
EP-4322915-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS Momentive Performance Materials Inc. (US) 2024-02-21 EP claimed
CN-117425467-A Personal care compositions comprising silicone based 迈图高新材料公司 2024-01-19 CN claimed
US-20230055665-A1 DELIVERY CARRIER INTO CELL ITO, KABUSIKIKAISYA (JP) 2023-02-23 US claimed
WO-2023009315-A1 A SUNSCREEN COMPOSITION COMPRISING AVOBENZONE AND A METHOD FOR PHOTOSTABILIZATION ISP INVESTMENTS LLC (US) 2023-02-02 WO claimed
WO-2022221354-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2022-10-20 WO claimed
CN-115135307-A Carrier for cell delivery 株式会社ITO 2022-09-30 CN claimed
CN-112914020-A Aqueous clear oil-in-water emulsions containing emulsified carotenoids 巴斯夫欧洲公司 2021-06-08 CN claimed
EP-1595936-A1 ANTIOXIDATIVE COMPOSITION AND COMPOSITION FOR EXTERNAL USE MITSUBISHI CORPORATION (JP) 2005-11-16 EP claimed
US-20050249689-A1 Personal care compositions with enhanced properties, method of manufacture, and method of use thereof MOMENTIVE PERFORMANCE MATERIALS INC. 2005-11-10 US claimed
US-20050249690-A1 Personal care compositions with enhanced properties, method of manufacture, and method of use thereof MOMENTIVE PERFORMANCE MATERIALS INC. 2005-11-10 US claimed
EP-1107728-B1 COSMETIC COMPOSITIONS FOR SOLAR PROTECTION AND USES OREAL (FR) 2004-04-28 EP claimed
EP-1002523-B1 Cosmetic sunscreening compositions OREAL (FR) 2004-03-03 EP claimed
US-20040028642-A1 Cosmetic composition comprising an extract of emblica officinalis and methods of using same L'OREAL S.A. (FR) 2004-02-12 US claimed
US-20020131939-A1 Hair protection compositions ROCHE VITAMINS INC. 2002-09-19 US claimed
US-6409999-B2 Synergistically UV-photoprotecting benzotriazole-substituted silicon/cinnamic acid compositions SOCIETE L'OREAL (FR) 2002-06-25 US claimed
US-20010041167-A1 Synergistically UV-photoprotecting benzotriazole-substituted silicon/cinnamic acid compositions SOCIETE L'OREAL S.A. (FR) 2001-11-15 US claimed
US-6143282-A TOPICAL APPLYING SOCIETE L'OREAL S.A. (FR) 2000-11-07 US claimed