SCHEMBL645927

SCHEMBL645927

COC(=O)/C=C/c1ccc(C(C)C)cc1C(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
KDM4E B2RXH2 5/20 0.48
MAPT P10636 3/20 0.48
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
TP53 P04637 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
CYP2C19 P33261 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TYR P14679 3/20 0.42
TTR P02766 1/20 0.42
APP P05067 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29435132 1.00 ALDH1A1 (0.48) ALDH1A1KDM4EMAPTKMT2AMEN1
SCHEMBL157462 1.00 ALDH1A1 (0.48) ALDH1A1KDM4EMAPTKMT2AMEN1
SCHEMBL647921 0.88 ALDH1A1 (0.48) ALDH1A1KDM4EMAPTKMT2AMEN1
SCHEMBL29520699 0.88 ALDH1A1 (0.48) ALDH1A1KDM4EMAPTKMT2AMEN1
SCHEMBL156609 0.88 ALDH1A1 (0.48) ALDH1A1KDM4EMAPTKMT2AMEN1
E-Methyl Cinnamate SCHEMBL28948986 0.88 KDM4E (0.51) KDM4EKMT2ATYRTTRAPP
E-Methyl Cinnamate SCHEMBL28810582 0.88 KDM4E (0.51) KDM4EKMT2ATYRTTRAPP
SCHEMBL25211344 0.87 CA12 (0.48) KDM4EMAPTTYRCA12CA1
SCHEMBL15514 0.84 TYR (0.50) MAPTTYRTTRCA12CA1
SCHEMBL648606 0.84 TYR (0.50) MAPTTYRTTRCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 657 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230055665-A1 DELIVERY CARRIER INTO CELL ITO, KABUSIKIKAISYA (JP) 2023-02-23 US claimed
CN-115135307-A Carrier for cell delivery 株式会社ITO 2022-09-30 CN claimed
CN-101282708-B External preparation for skin containing a phosphorlated saccharide EZAKI GLICO CO 2013-03-20 CN claimed
US-8168227-B2 Modified powder and cosmetic composition using the same SHISEIDO CO., LTD. (JP) 2012-05-01 US claimed
US-20070253989-A1 Modified Powder and Cosmetic Composition Using the Same SHISEIDO CO., LTD. (JP) 2007-11-01 US claimed
US-12564549-B2 Cleanser composition SHISEIDO COMPANY, LTD. (JP) 2026-03-03 US disclosed
US-20250295566-A1 DIESTER HAIR STYLING FORMULATIONS, AND USES THEREOF Chembeau LLC 2025-09-25 US disclosed
US-20250248913-A1 HAIR TREATMENT FORMULATIONS AND USES THEREOF Chembeau LLC 2025-08-07 US disclosed
US-20250177270-A1 DIESTER COSMETIC FORMULATIONS AND USES THEREOF Chembeau LLC 2025-06-05 US disclosed
WO-2025105415-A1 MELANOGENESIS INHIBITOR AND EXTERNAL PREPARATION FOR SKIN CONTAINING SAME 三菱瓦斯化学株式会社 2025-05-22 WO disclosed
US-12285508-B2 Hair treatment formulations and uses thereof Chembeau LLC (US) 2025-04-29 US disclosed
WO-2025041528-A1 OILY SOLID COSMETIC AND HARDNESS IMPROVER FOR OILY SOLID COSMETIC 日清オイリオグループ株式会社 2025-02-27 WO disclosed
EP-0721484-B1 ULTRAVIOLET SHIELDING COMPOSITE FINE PARTICLES, METHOD FOR PRODUCING THE SAME, AND COSMETICS KAO CORP (JP) 1998-06-17 EP disclosed
CN-1183038-A Ultraviolet-shielding composite fine particles, method for producing same, and cosmetic KAO CORP (JP) 1998-05-27 CN disclosed
US-5747049-A AMINOETHYLSULFINIC ACID OR AMINOETHYLTHIOSULFONIC ACID, SUNSCREEN SHISEIDO COMPANY, LTD. (JP) 1998-05-05 US disclosed
EP-0814758-A1 ULTRAVIOLET SHIELDING COMPOSITE FINE PARTICLES, METHOD FOR PRODUCING THE SAME, AND COSMETICS Kao Corporation (JP) 1998-01-07 EP disclosed
WO-1996028137-A1 ULTRAVIOLET SHIELDING COMPOSITE FINE PARTICLES, METHOD FOR PRODUCING THE SAME, AND COSMETICS KAO CORPORATION (JP) 1996-09-19 WO disclosed
EP-0688559-A1 Skin anti-ageing composition SHISEIDO COMPANY LIMITED (JP) 1995-12-27 EP disclosed
US-5000937-A Transparent cosmetic composition that reflects infrared radiation and its use for protecting the human epidermis against infrared radiation L'OREAL (FR) 1991-03-19 US disclosed
EP-0211183-A2 Use of ubidecarenone(ubiquinone-10) as an antichromatotic agent Eisai Co., Ltd. (JP) 1987-02-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250295566-A1 DIESTER HAIR STYLING FORMULATIONS, AND USES THEREOF SUCLG1, SMS, SRM ALDH1A1 1768/4885KDM4E 1831/4885MAPT 1660/4885
US-20230055665-A1 DELIVERY CARRIER INTO CELL CTSA, ATG4A, ATG7 ALDH1A1 2228/4885KDM4E 3872/4885MAPT 1714/4885
US-12564549-B2 Cleanser composition LIPA, SGMS1, SGMS2 ALDH1A1 4105/4885KDM4E 4122/4885MAPT 4799/4885
US-20250248913-A1 HAIR TREATMENT FORMULATIONS AND USES THEREOF FHIT, SUCLG1, TES ALDH1A1 834/4885KDM4E 1194/4885MAPT 2315/4885
US-12285508-B2 Hair treatment formulations and uses thereof FHIT, SUCLG1, TES ALDH1A1 834/4885KDM4E 1194/4885MAPT 2315/4885
US-20250177270-A1 DIESTER COSMETIC FORMULATIONS AND USES THEREOF DAGLA, CYP19A1, CYP51A1 ALDH1A1 242/4885KDM4E 4209/4885MAPT 2360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.