Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 8/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR1E | P28566 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.42 |
| ▸ | MTOR | P42345 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15747763 | 0.89 | PIK3CA (0.42) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL15747834 | 0.87 | MTOR (0.58) | ADORA2AADORA2BPIK3CAMTORPIK3CD | |
| SCHEMBL15747829 | 0.86 | LNPEP (0.45) | ADORA2AADORA2BTMEM97SIGMAR1PIK3CA | |
| SCHEMBL15747866 | 0.84 | MAPT (0.44) | ADORA2AADORA2BTMEM97SIGMAR1HTR1A | |
| SCHEMBL15747852 | 0.80 | MTOR (0.41) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL15747730 | 0.77 | MTOR (0.55) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL15747839 | 0.76 | CA1 (0.44) | TMEM97SIGMAR1HTR1AADRA2AADRA2B | |
| SCHEMBL15747772 | 0.76 | MTOR (0.55) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL15747795 | 0.75 | MTOR (0.55) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL15747812 | 0.75 | MTOR (0.57) | PIK3CAMTORPIK3CDPIK3CGPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014079364-A1 | IMIDAZOLONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | 北京富龙康泰生物技术有限公司 (CN) | 2014-05-30 | — | — | WO | disclosed |