Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15747820 | 0.88 | LNPEP (0.41) | LNPEPGRM5BTKROCK2PRMT1 | |
| SCHEMBL15747839 | 0.84 | CA1 (0.44) | CYP2C19SMN1; SMN2AURKBHDAC1 | |
| SCHEMBL15747732 | 0.83 | SMN1; SMN2 (0.46) | CYP2C19SMN1; SMN2AURKBHDAC1 | |
| SCHEMBL15747864 | 0.80 | HDAC1 (0.37) | ROCK2CYP2C19SMN1; SMN2AURKBCSF1R | |
| SCHEMBL15747829 | 0.77 | LNPEP (0.45) | LNPEPGRM5BTKAURKBCSF1R | |
| SCHEMBL15747824 | 0.77 | LNPEP (0.43) | LNPEPGRM5BTKPRMT1 | |
| SCHEMBL2674542 | 0.74 | LNPEP (0.51) | LNPEPGRM5PRMT1CYP2C19SMN1; SMN2 | |
| SCHEMBL15747743 | 0.74 | LNPEP (0.54) | LNPEPGRM5PRMT1CYP2C19SMN1; SMN2 | |
| SCHEMBL171387 | 0.73 | GRM5 (0.48) | LNPEPGRM5BTKPRMT1CYP2C19 | |
| SCHEMBL13490532 | 0.72 | GRM5 (0.52) | LNPEPGRM5BTKPRMT1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014079364-A1 | IMIDAZOLONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | 北京富龙康泰生物技术有限公司 (CN) | 2014-05-30 | — | — | WO | disclosed |