Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15747866 | 0.86 | MAPT (0.44) | HSD17B10POLBKDM4EALDH1A1USP2 | |
| SCHEMBL15747829 | 0.85 | LNPEP (0.45) | LNPEPGRM5MTORPIK3CABTK | |
| SCHEMBL15747771 | 0.84 | GRIN2B (0.42) | HSD17B10MTORPIK3CAMAPT | |
| SCHEMBL15747804 | 0.81 | MTOR (0.40) | MTORPIK3CATMEM97SIGMAR1 | |
| SCHEMBL15747823 | 0.77 | LNPEP (0.44) | LNPEPGRM5BTKPRMT1 | |
| SCHEMBL15747795 | 0.75 | MTOR (0.55) | LNPEPMTORPIK3CA | |
| SCHEMBL18998180 | 0.75 | GABRA1 (0.54) | HSD17B10GAAKDM4EALDH1A1HPGD | |
| SCHEMBL15747820 | 0.74 | LNPEP (0.41) | LNPEPGRM5BTKOPRK1PRMT1 | |
| SCHEMBL15747855 | 0.74 | MTOR (0.49) | LNPEPMTORPIK3CA | |
| SCHEMBL15747788 | 0.72 | MTOR (0.50) | LNPEPMTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014079364-A1 | IMIDAZOLONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | 北京富龙康泰生物技术有限公司 (CN) | 2014-05-30 | — | — | WO | disclosed |