Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 13/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | RAF1 | P04049 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.79 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.79 |
| ▸ | PKM | P14618 | 3/20 | 0.79 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.79 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Sulfoxide SCHEMBL28821807 | 0.92 | AR (0.84) | ARCYP3A4KMT2AMAPTMEN1 | |
| Chrysin SCHEMBL5461671 | 0.89 | CYP3A4 (0.82) | ARCYP3A4KMT2AMAPTMEN1 | |
| 5-Hydroxyflavone SCHEMBL158303 | 0.89 | AR (1.00) | ARCYP3A4KMT2AMAPTMEN1 | |
| 5-Hydroxyflavone SCHEMBL30630415 | 0.89 | AR (1.00) | ARCYP3A4KMT2AMAPTMEN1 | |
| 5-Hydroxyflavone SCHEMBL2390993 | 0.89 | AR (1.00) | ARCYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL6097859 | 0.88 | AR (1.00) | ARCYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL12636899 | 0.88 | AR (1.00) | ARCYP3A4KMT2AMAPTMEN1 | |
| 5-Hydroxyflavone SCHEMBL28317755 | 0.87 | AR (0.97) | ARCYP3A4KMT2AMAPTMEN1 | |
| 5-Hydroxyflavone SCHEMBL2390943 | 0.87 | AR (0.97) | ARCYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL6094870 | 0.87 | CYP3A4 (0.85) | ARCYP3A4KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250195452-A1 | ER-BETA ESTROGENIC COMPOUNDS AND METHODS OF USE | IATERION, INC. | 2025-06-19 | — | — | US | claimed |
| EP-4561582-A1 | ER-BETA ESTROGENIC COMPOUNDS AND METHODS OF USE | Iaterion, Inc. (US) | 2025-06-04 | — | — | EP | claimed |
| CN-119604294-A | ERbeta estrogenic compounds and methods of use | 益特瑞恩公司 | 2025-03-11 | — | — | CN | claimed |
| CN-117562061-A | PH value intelligent sensing algae-inhibiting flavone slow-release microsphere and preparation method thereof | 浙江大学 | 2024-02-20 | — | — | CN | claimed |
| CN-117562060-A | Temperature intelligent sensing algae-inhibiting flavone slow-release microsphere and preparation method thereof | 浙江大学 | 2024-02-20 | — | — | CN | claimed |
| WO-2024026037-A1 | ER-BETA ESTROGENIC COMPOUNDS AND METHODS OF USE | IATERION, INC. (US) | 2024-02-01 | — | — | WO | claimed |
| WO-2023150072-A1 | COMPOSITIONS AND METHODS FOR THE PRESERVATION OF PLANT MATTER | SINCLAIR DAVID A (US) | 2023-08-10 | — | — | WO | claimed |
| US-20160367497-A1 | METHODS AND COMPOSITIONS FOR TREATING NEUROPATHIES | WASHINGTON UNIVERSITY | 2016-12-22 | — | — | US | claimed |
| EP-2670404-A1 | SIRTUIN MODULATORS AS VIRUS PRODUCTION MODULATORS | The Trustees of Princeton University (US) | 2013-12-11 | — | — | EP | claimed |
| CN-103391777-A | Sirtuin modulators as virus production modulators | UNIV PRINCETON | 2013-11-13 | — | — | CN | claimed |
| WO-2006045096-A2 | FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | RESVERLOGIX CORP. (CA) | 2006-04-27 | — | — | WO | claimed |
| US-20060002914-A1 | treating or preventing axonal degradation in neuropathic diseases in mammals; axonopathy; administering an agent (such as NAD, NADH) that increases sirtuin activity in diseased and/or injured neurons and supporting cells in an amount effective to decrease axonal degeneration | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-01-05 | — | — | US | claimed |
| WO-2006001982-A2 | METHODS AND COMPOSITIONS FOR TREATING NEUROPATHIES | WASHINGTON UNIVERSITY (US) | 2006-01-05 | — | — | WO | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| WO-2003026705-A1 | METHODS FOR STERILIZING BIOLOGICAL MATERIALS USING FLAVONOID/FLAVONOL STABILIZERS | CLEARANT, INC. (US) | 2003-04-03 | — | — | WO | claimed |
| US-20030059338-A1 | Methods for sterilizing biological materials using flavonoid/flavonol stabilizers | CLEARANT, INC. | 2003-03-27 | — | — | US | claimed |
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250195452-A1 | ER-BETA ESTROGENIC COMPOUNDS AND METHODS OF USE | ESR2, ESR1, ESRRB | AR 26/4885CYP3A4 210/4885KMT2A 4051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.