Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.85 |
| ▸ | MAPT | P10636 | 4/20 | 0.85 |
| ▸ | AR | P10275 | 12/20 | 0.84 |
| ▸ | MEN1 | O00255 | 4/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.84 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.84 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.84 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.84 |
| ▸ | PKM | P14618 | 1/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.84 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.84 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.84 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.79 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.79 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.79 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649971 | 0.92 | CYP3A4 (1.00) | CYP3A4MAPTARMEN1KMT2A | |
| 5-Hydroxyflavone SCHEMBL2390993 | 0.92 | AR (1.00) | CYP3A4MAPTARMEN1KMT2A | |
| 5-Hydroxyflavone SCHEMBL30630415 | 0.92 | AR (1.00) | CYP3A4MAPTARMEN1KMT2A | |
| 5-Hydroxyflavone SCHEMBL158303 | 0.92 | AR (1.00) | CYP3A4MAPTARMEN1KMT2A | |
| 5-Hydroxyflavone SCHEMBL2390943 | 0.90 | AR (0.97) | CYP3A4MAPTARMEN1KMT2A | |
| 5-Hydroxyflavone SCHEMBL28317755 | 0.90 | AR (0.97) | CYP3A4MAPTARMEN1KMT2A | |
| SCHEMBL3817277 | 0.89 | CYP3A4 (1.00) | CYP3A4MAPTARMEN1KMT2A | |
| SCHEMBL30591245 | 0.89 | CYP3A4 (1.00) | CYP3A4MAPTARMEN1KMT2A | |
| SCHEMBL157490 | 0.87 | AR (1.00) | CYP3A4MAPTARMEN1KMT2A | |
| SCHEMBL3817662 | 0.87 | CYP3A4 (0.75) | CYP3A4MAPTARMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009062-B2 | Process for the preparation of flavone derivatives | MERCK PATENT GMBH (DE) | 2006-03-07 | — | — | US | disclosed |
| EP-1355898-B1 | METHOD FOR PRODUCING FLAVONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2005-10-12 | — | — | EP | disclosed |
| US-20040059100-A1 | Process for the preparation of flavone derivatives | EUROPEAN BRAND PARTICIPATIONS SA (LU) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040059100-A1 | Process for the preparation of flavone derivatives | HK2, MAP2K5, MAP2K4 | CYP3A4 38/4885MAPT 842/4885AR 2913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.