Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 5/20 | 0.62 |
| ▸ | FAAH | O00519 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.57 |
| ▸ | CCR2 | P41597 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1575714 | 0.92 | FAAH (0.60) | CCR3FAAHSMN1; SMN2MEN1KMT2A | |
| SCHEMBL17742829 | 0.89 | FAAH (0.77) | CCR3FAAHKDM4ENPC1MAPT | |
| SCHEMBL1575004 | 0.89 | FAAH (0.76) | CCR3FAAHSMN1; SMN2GRIN2BMEN1 | |
| SCHEMBL1575030 | 0.88 | FAAH (0.65) | CCR3FAAHKDM4ENPC1MAPT | |
| SCHEMBL1575818 | 0.88 | CCR3 (0.62) | CCR3FAAHNPC1SMN1; SMN2GRIN2B | |
| SCHEMBL1574680 | 0.88 | FAAH (0.80) | CCR3FAAHRAB9ASMN1; SMN2GRIN2B | |
| SCHEMBL1575322 | 0.86 | CCR3 (0.71) | CCR3FAAHSMN1; SMN2GRIN2BMEN1 | |
| SCHEMBL1575138 | 0.85 | CCR3 (0.59) | CCR3FAAHGRIN2BCCR2KCNH2 | |
| SCHEMBL1575231 | 0.85 | CCR3 (0.62) | CCR3FAAHMAPTSMN1; SMN2GRIN2B | |
| SCHEMBL1574855 | 0.84 | CCR3 (0.61) | CCR3FAAHSMN1; SMN2GRIN2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308562-A2 | Azetidine ring compounds and drugs comprising the same | Ono Pharmaceutical Co., Ltd. (JP) | 2011-04-13 | — | — | EP | disclosed |
| US-7511159-B2 | Azetidine ring compounds and drugs comprising the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-03-31 | — | — | US | disclosed |
| US-20070135402-A1 | Azetidine ring compounds and drugs comprising the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-06-14 | — | — | US | disclosed |
| EP-1698375-A1 | AZETIDINE RING COMPOUNDS AND DRUGS COMPRISING THE SAME | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135402-A1 | Azetidine ring compounds and drugs comprising the same | EDNRA, LIPG, EDNRB | CCR3 3504/4885FAAH 3484/4885KDM4E 516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.