Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | CCR3 | P51677 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1574908 | 0.89 | CCR3 (0.62) | FAAHSMN1; SMN2KDM4ENPC1MAPT | |
| SCHEMBL3600315 | 0.87 | FAAH (1.00) | FAAHSMN1; SMN2KDM4ECCR3MEN1 | |
| SCHEMBL13234936 | 0.86 | FAAH (0.82) | FAAHSMN1; SMN2KDM4ENPC1MAPT | |
| SCHEMBL14448415 | 0.86 | ALDH1A1 (0.58) | FAAHSMN1; SMN2KDM4ENPC1MAPT | |
| SCHEMBL3594301 | 0.86 | FAAH (1.00) | FAAHSMN1; SMN2RAB9ACCR3MEN1 | |
| SCHEMBL18862012 | 0.86 | FAAH (0.77) | FAAHSMN1; SMN2NPC1CCR3MEN1 | |
| SCHEMBL13713102 | 0.84 | MEN1 (0.67) | FAAHSMN1; SMN2KDM4ENPC1MAPT | |
| SCHEMBL5527835 | 0.84 | ALDH1A1 (0.56) | FAAHSMN1; SMN2KDM4ENPC1MAPT | |
| SCHEMBL5527838 | 0.84 | ALDH1A1 (0.56) | FAAHSMN1; SMN2KDM4ENPC1MAPT | |
| SCHEMBL830207 | 0.82 | FAAH (0.74) | FAAHSMN1; SMN2CCR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3215142-B1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2021-03-24 | — | — | EP | disclosed |
| US-10206893-B2 | Immunoregulatory agents | FLEXUS BIOSCIENCES, INC. (US) | 2019-02-19 | — | — | US | disclosed |
| US-20170143649-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2017-05-25 | — | — | US | disclosed |
| US-9598422-B2 | Immunoregulatory agents | FLEXUS BIOSCIENCES, INC. (US) | 2017-03-21 | — | — | US | disclosed |
| US-20160137653-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES, INC. | 2016-05-19 | — | — | US | disclosed |
| WO-2016073774-A2 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES, INC. (US) | 2016-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137653-A1 | IMMUNOREGULATORY AGENTS | IDO1, IDO2, INMT | FAAH 930/4885SMN1; SMN2 4584/4885KDM4E 2099/4885 |
| US-10206893-B2 | Immunoregulatory agents | IDO1, IDO2, INMT | FAAH 930/4885SMN1; SMN2 4584/4885KDM4E 2099/4885 |
| US-20170143649-A1 | IMMUNOREGULATORY AGENTS | IDO1, IDO2, INMT | FAAH 930/4885SMN1; SMN2 4584/4885KDM4E 2099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.