SCHEMBL157491

SCHEMBL157491

CC(C)c1cc(Nc2ccccc2)ccc1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.48
MAPT P10636 9/20 0.48
CYP3A4 P08684 7/20 0.48
HSD17B10 Q99714 7/20 0.48
ALOX12 P18054 5/20 0.48
ALOX15 P16050 5/20 0.48
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
TDP1 Q9NUW8 4/20 0.48
LMNA P02545 4/20 0.48
TSHR P16473 4/20 0.48
HPGD P15428 4/20 0.48
GAA P10253 4/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
THRB P10828 3/20 0.48
KDM4E B2RXH2 3/20 0.48
RECQL P46063 2/20 0.48
GFER P55789 2/20 0.48
ATM Q13315 1/20 0.48
CYP1A2 P05177 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3689775 0.82 ALDH1A1 (0.51) ALDH1A1MAPTCYP3A4HSD17B10ALOX12
SCHEMBL18109165 0.81 ALDH1A1 (0.43) ALDH1A1MAPTCYP3A4HSD17B10ALOX12
SCHEMBL5340425 0.79 ALDH1A1 (0.45) ALDH1A1MAPTCYP3A4HSD17B10ALOX12
SCHEMBL28228619 0.77 ALDH1A1 (0.47) ALDH1A1MAPTCYP3A4HSD17B10ALOX12
SCHEMBL5088671 0.77 ALDH1A1 (0.60) ALDH1A1MAPTCYP3A4HSD17B10ALOX12
SCHEMBL2127369 0.76 ALDH1A1 (0.70) ALDH1A1MAPTCYP3A4HSD17B10ALOX12
SCHEMBL30998047 0.76 ALDH1A1 (0.70) ALDH1A1MAPTCYP3A4HSD17B10ALOX12
SCHEMBL3895691 0.75 ALDH1A1 (0.46) ALDH1A1MAPTCYP3A4HSD17B10ALOX12
Benzene SCHEMBL27545048 0.72 ANPEP (0.41) ALDH1A1MAPTCYP3A4HSD17B10ALOX12
SCHEMBL9515040 0.72 HSD17B10 (0.47) ALDH1A1MAPTCYP3A4HSD17B10ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3749709-A1 PROCESS FOR VULCANIZING A REINFORCED RUBBER COMPOSITION Nouryon Chemicals International B.V. (NL) 2020-12-16 EP claimed
EP-3634939-A1 METHODS OF MAKING COMPOUNDS HAVING ANTIDEGRADANT AND ANTIFATIGUE EFFICACY Eastman Chemical Company (US) 2020-04-15 EP claimed
WO-2019154825-A1 PROCESS FOR VULCANIZING A REINFORCED RUBBER COMPOSITION NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2019-08-15 WO claimed
WO-2018226372-A1 METHODS OF MAKING COMPOUNDS HAVING ANTIDEGRADANT AND ANTIFATIGUE EFFICACY EASTMAN CHEMICAL COMPANY (US) 2018-12-13 WO claimed
EP-1976821-A1 DIRECT ALKYLATION OF N-ALKYL-N'-PHENYL-P-PHENYLENEDIAMINE CHEMTURA CORPORATION (US) 2008-10-08 EP claimed
WO-2007087195-A1 DIRECT ALKYLATION OF N-ALKYL-N'-PHENYL-P-PHENYLENEDIAMINE CHEMTURA CORPORATION (US) 2007-08-02 WO claimed
JP-59113043-A None JP disclosed
JP-11315165-A None JP disclosed
JP-1135843-A None JP disclosed
JP-54110261-A None JP disclosed
US-20240417500-A1 Modified Conjugated Diene-Based Polymer, Method for Preparing the Same and Rubber Composition Including the Same LG CHEM, LTD. (KR) 2024-12-19 US disclosed
EP-4396283-A1 COMPOSITE MATERIAL FOR VEHICLE TIRES, AND METHOD FOR PRODUCING SAME Continental Reifen Deutschland GmbH (DE) 2024-07-10 EP disclosed
EP-4395979-A1 COMPOSITE MATERIAL AS ABRASION PROTECTION FOR VEHICLE TIRES, AND PRODUCTION METHOD Continental Reifen Deutschland GmbH (DE) 2024-07-10 EP disclosed
US-5120280-A Used in automotive industries; heat, wear and cracking resistance MITSUBOSHI BELTING LTD. (JP) 1992-06-09 US disclosed
EP-0413305-A1 Chlorosulfonated polyethylene polymer composition TOSOH CORPORATION (JP) 1991-02-20 EP disclosed
EP-0405216-A1 Rubber composition containing a sulfur-modified polychloroprene gel BAYER AG (DE) 1991-01-02 EP disclosed
JP-H01135843-A RUBBER COMPOSITION FOR TIRE TREAD YOKOHAMA RUBBER CO LTD:THE 1989-05-29 JP disclosed
EP-0232907-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-08-19 EP disclosed
JP-S59113043-A MATERIAL FOR CONVEYOR BELT BRIDGESTONE CORP 1984-06-29 JP disclosed
JP-S54110261-A AROMATIC PETROLEUM RESIN COMPOSITION TOYO SODA MFG CO LTD 1979-08-29 JP disclosed