SCHEMBL2127369

SCHEMBL2127369

Cc1cc(Nc2ccccc2)ccc1N

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.70
TDP1 Q9NUW8 6/20 0.70
CYP3A4 P08684 6/20 0.70
ALOX15 P16050 3/20 0.70
THRB P10828 3/20 0.70
RECQL P46063 2/20 0.70
HIF1A Q16665 1/20 0.70
MAPT P10636 6/20 0.54
L3MBTL1 Q9Y468 4/20 0.54
ALOX12 P18054 3/20 0.54
HPGD P15428 3/20 0.54
CYP1A2 P05177 3/20 0.54
CYP2C9 P11712 2/20 0.54
CYP2C19 P33261 2/20 0.54
HTT P42858 1/20 0.54
LMNA P02545 4/20 0.53
GAA P10253 4/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
KDM4E B2RXH2 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30998047 1.00 ALDH1A1 (0.70) ALDH1A1TDP1CYP3A4ALOX15THRB
SCHEMBL11511767 0.89 CYP3A4 (0.77) ALDH1A1TDP1CYP3A4ALOX15THRB
SCHEMBL22701365 0.86 ALDH1A1 (0.72) ALDH1A1TDP1CYP3A4ALOX15THRB
SCHEMBL29764083 0.85 CYP3A4 (0.71) ALDH1A1TDP1CYP3A4ALOX15THRB
SCHEMBL29709 0.85 CYP3A4 (0.71) ALDH1A1TDP1CYP3A4ALOX15THRB
SCHEMBL3792803 0.85 CYP3A4 (0.61) ALDH1A1TDP1CYP3A4ALOX15THRB
SCHEMBL9651411 0.84 ALDH1A1 (0.54) ALDH1A1TDP1CYP3A4ALOX15THRB
SCHEMBL30826545 0.84 ALDH1A1 (0.54) ALDH1A1TDP1CYP3A4ALOX15THRB
SCHEMBL30826546 0.84 ALDH1A1 (0.54) ALDH1A1TDP1CYP3A4ALOX15THRB
SCHEMBL5495313 0.83 ALDH1A1 (0.50) ALDH1A1TDP1CYP3A4ALOX15THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106608827-A Preparation method for aryl substituted p-phenylenediamine substance 江苏圣奥化学科技有限公司 2017-05-03 CN claimed
EP-1656551-A1 LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR Honeywell International Inc. (US) 2006-05-17 EP claimed
WO-2005019816-A1 LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR HONEYWELL INTERNATIONAL, INC. (US) 2005-03-03 WO claimed
US-20050042758-A1 Leak detection method using microencapsulated dye precursor HONEYWELL CORPORATION 2005-02-24 US claimed
US-4692397-A SUBSTRATE COATED WITH A DIAZONIUM SALT; COLORANT AND A POLYVINYL ACETAL RESIN; LITHOGRAPHIC PRINTING PLATES AMERICAN HOECHST CORPORATION (US) 1987-09-08 US claimed
US-4661432-A Light-sensitive, diazonium group-containing polycondensation product, process for its production, and light-sensitive recording material containing this polycondensation product HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-28 US claimed
US-20250368607-A1 QUINOLINEAMINE ANTIDEGRADANT COMPOUNDS AND USES THEREOF FLEXSYS AMERICA LP (US) 2025-12-04 US disclosed
CN-119698282-A Quinoline amine degradation-resistant compound and application thereof 弗莱克斯塞思美国有限合伙公司 2025-03-25 CN disclosed
WO-2023235855-A1 QUINOLINEAMINE ANTIDEGRADANT COMPOUNDS AND USES THEREOF FLEXSYS AMERICA L.P. (US) 2023-12-07 WO disclosed
CN-114846080-A Thermoplastic molding compositions containing polyalkylene terephthalates 巴斯夫欧洲公司 2022-08-02 CN disclosed
WO-2021122715-A1 THERMOPLASTIC MOULDING COMPOSITION CONTAINING POLYALKYLENE TEREPHTHALATE BASF SE (DE) 2021-06-24 WO disclosed
CN-108137806-B Polyimide precursor, polyimide having crosslinked structure, and method for producing same 宇部兴产株式会社 2021-05-28 CN disclosed
CN-111234219-B Polyimide precursor, polyimide having crosslinked structure, and method for producing same 宇部兴产株式会社 2021-05-28 CN disclosed
EP-0126875-B1 LIGHT-SENSITIVE POLYCONDENSATION PRODUCT WITH DIAZONIUM GROUPS, PROCESS FOR THE PREPARATION THEREOF AND LIGHT-SENSITIVE REGISTRATION MATERIAL WHICH CONTAINS THIS POLYCONDENSATION PRODUCT HOECHST AKTIENGESELLSCHAFT (DE) 1987-05-27 EP disclosed
US-4661432-A Light-sensitive, diazonium group-containing polycondensation product, process for its production, and light-sensitive recording material containing this polycondensation product HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-28 US disclosed
EP-0074580-B1 LIGHT-SENSITIVE POLYCONDENSATION PRODUCT COMPRISING DIAZONIUM GROUPS, AND LIGHT-SENSITIVE RECORDING MATERIAL MADE THEREFROM HOECHST AKTIENGESELLSCHAFT (DE) 1986-12-03 EP disclosed
US-4492748-A Light-sensitive polycondensation product containing diazonium and dialdehyde groups, and light-sensitive recording material prepared therewith HOECHST AKTIENGESELLSCHAFT, A CORP. OF GERMANY (DE) 1985-01-08 US disclosed
EP-0126875-A1 Light-sensitive polycondensation product with diazonium groups, process for the preparation thereof and light-sensitive registration material which contains this polycondensation product HOECHST AKTIENGESELLSCHAFT (DE) 1984-12-05 EP disclosed
EP-0074580-A2 Light-sensitive polycondensation product comprising diazonium groups, and light-sensitive recording material made therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1983-03-23 EP disclosed
US-4186017-A Light-sensitive copying composition HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368607-A1 QUINOLINEAMINE ANTIDEGRADANT COMPOUNDS AND USES THEREOF FOXM1, TOP2B, SETD1B ALDH1A1 1925/4885TDP1 43/4885CYP3A4 877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.