SCHEMBL3689775

SCHEMBL3689775

CC(C)CC(C)c1cc(Nc2ccccc2)ccc1N

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.51
CYP3A4 P08684 7/20 0.51
HSD17B10 Q99714 7/20 0.51
ALOX12 P18054 5/20 0.51
ALOX15 P16050 5/20 0.51
TSHR P16473 4/20 0.51
MAPK1 P28482 3/20 0.51
HIF1A Q16665 2/20 0.51
MAPT P10636 7/20 0.42
MEN1 O00255 6/20 0.42
KMT2A Q03164 6/20 0.42
LMNA P02545 4/20 0.42
TDP1 Q9NUW8 4/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
THRB P10828 3/20 0.42
KDM4E B2RXH2 3/20 0.42
GAA P10253 3/20 0.42
RECQL P46063 2/20 0.42
ATM Q13315 1/20 0.42
GFER P55789 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18109165 0.87 ALDH1A1 (0.43) ALDH1A1CYP3A4HSD17B10ALOX12ALOX15
SCHEMBL157491 0.82 ALDH1A1 (0.48) ALDH1A1CYP3A4HSD17B10ALOX12ALOX15
SCHEMBL5340425 0.81 ALDH1A1 (0.45) ALDH1A1CYP3A4HSD17B10ALOX12ALOX15
SCHEMBL28282147 0.76 ALDH1A1 (0.44) ALDH1A1CYP3A4HSD17B10ALOX12ALOX15
SCHEMBL14804257 0.75 ALDH1A1 (0.62) ALDH1A1CYP3A4HSD17B10ALOX12ALOX15
SCHEMBL3895691 0.75 ALDH1A1 (0.46) ALDH1A1CYP3A4HSD17B10ALOX12ALOX15
SCHEMBL3337211 0.75 ALDH1A1 (0.51) ALDH1A1CYP3A4HSD17B10ALOX12ALOX15
SCHEMBL28282143 0.75 MAPT (0.46) ALDH1A1CYP3A4HSD17B10ALOX12ALOX15
SCHEMBL15093601 0.74 TDP1 (0.51) ALDH1A1CYP3A4HSD17B10ALOX12ALOX15
SCHEMBL7089523 0.73 ALDH1A1 (0.38) ALDH1A1CYP3A4HSD17B10ALOX12ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210292649-A1 COMPOSITION SI GROUP, INC. 2021-09-23 US claimed
CN-112778593-A Semi-hot-melt tread rubber composition and asphalt Racing tire 正新橡胶(中国)有限公司 2021-05-11 CN claimed
CN-112469776-A Composition comprising a metal oxide and a metal oxide 瑞士新集团有限公司 2021-03-09 CN claimed
US-6184283-B1 LOW ELECTRICAL RESISTANCE, LOW ROLLING RESISTANCE, ABRASION RESISTANCE AND GOOD WET PERFORMANCE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2001-02-06 US claimed
EP-3916045-B1 HIGH STRENGTH HYDROGENATED POLYMERS, AND RUBBER COMPOSITIONS INCORPORATING SAME BRIDGESTONE CORP (JP) 2026-05-06 EP disclosed
US-12577370-B2 Non-dust blend SI GROUP, INC. (US) 2026-03-17 US disclosed
US-20250296943-A1 AMINE-CONTAINING VINYLDISILOXANES IN THE MANUFACTURE OF ELASTOMERIC POLYMERS SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (PL) 2025-09-25 US disclosed
EP-4610358-A1 FAD-DEPENDENT GLUTAMATE DEHYDROGENASE Kikkoman Corporation (JP) 2025-09-03 EP disclosed
US-20250263524-A1 Method for Polycondensation of a Recycled Polyester SI GROUP, INC. 2025-08-21 US disclosed
US-12320059-B2 Adducts between carbon allotropes and pyrrole derivatives, elastomer mixtures comprising them and tyres comprising such mixtures PIRELLI TYRE S.P.A. (IT) 2025-06-03 US disclosed
EP-4559967-A1 RUBBER MIXTURES CONTAINING AT LEAST ONE PROCESS AID OF FORMULA (I) LANXESS Deutschland GmbH (DE) 2025-05-28 EP disclosed
CN-115210311-B Dust free blends 瑞士新集团股份有限公司 2024-06-18 CN disclosed
US-6114554-A Preparation of quinonediimines from phenylenediamines using a hypochlorite as an oxidation agent FLEXSYS AMERICA L.P. (US) 2000-09-05 US disclosed
EP-1030833-A1 PREPARATION OF QUINONEDIIMINES FROM PHENYLENEDIAMINES USING A HYPOCHLORITE AS AN OXIDATION AGENT FLEXSYS AMERICA L.P. (US) 2000-08-30 EP disclosed
EP-0928810-A2 Rubber composition for a tyre tread SUMITOMO RUBBER INDUSTRIES LTD. (JP) 1999-07-14 EP disclosed
WO-1999021826-A1 PREPARATION OF QUINONEDIIMINES FROM PHENYLENEDIAMINES USING A HYPOCHLORITE AS AN OXIDATION AGENT FLEXSYS AMERICA L.P. (US) 1999-05-06 WO disclosed
EP-0039408-B1 RUBBER SKIM STOCK WITH IMPROVED ADHESION TO A BRASS COATED METAL MEMBER THE FIRESTONE TIRE & RUBBER COMPANY (US) 1985-07-17 EP disclosed
US-4324281-A Method, composition and product employing a tetracarboxylic dianhydride to improve adhesion between a metal member and a contiguous rubber skim stock THE FIRESTONE TIRE & RUBBER COMPANY (US) 1982-04-13 US disclosed
EP-0039408-A2 Rubber skim stock with improved adhesion to a brass coated metal member THE FIRESTONE TIRE & RUBBER COMPANY (US) 1981-11-11 EP disclosed
US-4195679-A Composition and product with improved adhesion between a metal member and a contiguous cured rubber skim stock THE FIRESTONE TIRE & RUBBER COMPANY (US) 1980-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210292649-A1 COMPOSITION GPX4, TXN2, TXNRD2 ALDH1A1 3658/4885CYP3A4 1018/4885HSD17B10 1957/4885
US-12320059-B2 Adducts between carbon allotropes and pyrrole derivatives, elastomer mixtures comprising them and tyres comprising such mixtures SELE, CCR2, SRMS ALDH1A1 1915/4885CYP3A4 2475/4885HSD17B10 4615/4885
US-20250296943-A1 AMINE-CONTAINING VINYLDISILOXANES IN THE MANUFACTURE OF ELASTOMERIC POLYMERS VARS1, VCL, TYK2 ALDH1A1 3134/4885CYP3A4 2329/4885HSD17B10 3526/4885
US-12577370-B2 Non-dust blend NONO, POT1, PTPN11 ALDH1A1 2150/4885CYP3A4 1075/4885HSD17B10 3815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.