Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL1393934 | 0.95 | STAT3 (0.40) | STAT3GAAKMT2ASMN1; SMN2F2 | |
| SCHEMBL157493 | 0.86 | GAA (0.42) | STAT3GAAKMT2ASMN1; SMN2F2 | |
| SCHEMBL4960150 | 0.85 | GAA (0.41) | STAT3GAAKMT2ASMN1; SMN2F2 | |
| SCHEMBL28684540 | 0.83 | PARL (0.40) | GAAKMT2ASMN1; SMN2ALDH1A1CA1 | |
| SCHEMBL3315459 | 0.82 | GAA (0.52) | STAT3GAAKMT2ASMN1; SMN2CYP2D6 | |
| Fluoride SCHEMBL31533364 | 0.80 | GAA (0.50) | STAT3GAAKMT2ASMN1; SMN2CYP2D6 | |
| SCHEMBL3165478 | 0.79 | STAT3 (0.44) | STAT3GAAKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL9905506 | 0.78 | C5AR1 (0.38) | STAT3GAAKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11604749 | 0.78 | GAA (0.48) | STAT3GAAKMT2ASMN1; SMN2CYP2D6 | |
| SCHEMBL3131297 | 0.77 | GAA (0.46) | STAT3GAAKMT2ASMN1; SMN2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894554-A | Preparation method of phosphonic acid compound | 烟台药物研究所 | 2023-04-04 | — | — | CN | claimed |
| US-5733896-A | VIRICIDE FOR RETROVIRUS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-03-31 | — | — | US | claimed |
| CN-120022913-A | Method for using high-stability copper-based catalyst in hydrochlorination of acetylene | 中盐吉兰泰氯碱化工有限公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-115894554-A | Preparation method of phosphonic acid compound | 烟台药物研究所 | 2023-04-04 | — | — | CN | disclosed |
| CN-115894554-A | Preparation method of phosphonic acid compound | 烟台药物研究所 | 2023-04-04 | — | — | CN | disclosed |
| EP-3020720-B1 | PHOSPHONATE ESTER DERIVATIVES AND METHODS OF SYNTHESIS THEREOF | CHIMERIX INC (US) | 2018-09-19 | — | — | EP | disclosed |
| CN-106687467-A | Method for preparing high-purity (r)-9-[2-(phosphonomethoxy)propyl]adenine | 韩美精密化学株式会社 | 2017-05-17 | — | — | CN | disclosed |
| CN-105998039-A | Phosphonate ester derivatives and methods of synthesis thereof | 奇默里克斯公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-102939291-B | Phosphonate ester for the toxicity with reduction for the treatment of of viral infections | 加利福尼亚大学董事会 | 2016-09-07 | — | — | CN | disclosed |
| EP-2611818-B1 | PHOSPHONATE ESTER DERIVATIVES AND METHODS OF SYNTHESIS THEREOF | CHIMERIX INC (US) | 2016-08-24 | — | — | EP | disclosed |
| CN-103209985-B | Phosphonate derivatives and methods of synthesis thereof | 奇默里克斯公司 | 2016-08-24 | — | — | CN | disclosed |
| EP-2611818-A2 | PHOSPHONATE ESTER DERIVATIVES AND METHODS OF SYNTHESIS THEREOF | Chimerix, Inc. (US) | 2013-07-10 | — | — | EP | disclosed |
| WO-2013072745-A1 | PROCESS FOR THE PREPARATION OF TENOFOVIR | LAURUS LABS PRIVATE LIMITED (IN) | 2013-05-23 | — | — | WO | disclosed |
| WO-2012081032-A1 | PROCESS FOR THE PREPARATION OF TENOFOVIR | APTUIT LAURUS PRIVATE LIMITED (IN) | 2012-06-21 | — | — | WO | disclosed |
| US-20120058976-A1 | Phosphonate Ester Derivatives and Methods of Synthesis Thereof | CHIMERIX, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| WO-2012031045-A2 | PHOSPHONATE ESTER DERIVATIVES AND METHODS OF SYNTHESIS THEREOF | CHIMERIX, INC. (US) | 2012-03-08 | — | — | WO | disclosed |
| EP-2086990-A2 | NOVEL NUCLEOTIDE ANALOGUES AS PERCURSOR MOLECULES FOR ANTIVIRALS | Centre National De La Recherche Scientifique-CNRS (FR) | 2009-08-12 | — | — | EP | disclosed |
| US-7388002-B2 | Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases | BIOCRYST PHARMACEUTICALS, INC. (US) | 2008-06-17 | — | — | US | disclosed |
| WO-2008056264-A2 | NOVEL NUCLEOTIDE ANALOGUES AS PERCURSOR MOLECULES FOR ANTIVIRALS | CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2008-05-15 | — | — | WO | disclosed |
| US-20060122391-A1 | Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases | BIOCRYST PHARMACEUTICALS, INC. (US) | 2006-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122391-A1 | Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases | POLR2H, NSUN2, POLR2E | STAT3 2322/4885GAA 2605/4885KMT2A 1027/4885 |
| US-20120058976-A1 | Phosphonate Ester Derivatives and Methods of Synthesis Thereof | PHOSPHO1, PIK3CA, PNP | STAT3 3774/4885GAA 507/4885KMT2A 2791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.