Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | ELANE | P08246 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30645929 | 1.00 | MEN1 (0.42) | MEN1KMT2AGAACNR1CNR2 | |
| SCHEMBL26604997 | 0.90 | KMT2A (0.36) | MEN1KMT2AGAACNR1CNR2 | |
| SCHEMBL9155082 | 0.84 | ALDH1A1 (0.57) | MEN1KMT2AGAAALDH1A1TDP1 | |
| SCHEMBL31014100 | 0.83 | ALDH1A1 (0.41) | GAAALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL26604721 | 0.83 | ALDH1A1 (0.41) | GAAALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL9282920 | 0.82 | TSHR (0.44) | KMT2AGAAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL31013939 | 0.81 | ALDH1A1 (0.40) | GAACNR1CNR2ALDH1A1TDP1 | |
| SCHEMBL26604993 | 0.79 | GLO1 (0.36) | MEN1KMT2AGAACNR1CNR2 | |
| SCHEMBL15348611 | 0.79 | TDP1 (0.58) | MEN1KMT2AGAAALDH1A1TDP1 | |
| SCHEMBL31013887 | 0.78 | ALDH1A1 (0.37) | GAAALDH1A1TDP1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140155635-A1 | RESORCYLIC ACID LACTONE COMPOUNDS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155635-A1 | RESORCYLIC ACID LACTONE COMPOUNDS | MCL1, PRKCA, REL | MEN1 2084/4885KMT2A 857/4885GAA 1431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.