Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601842 | 0.86 | TTR (0.49) | HSD17B1HSD17B2CYP3A4TTRESR1 | |
| SCHEMBL22182158 | 0.85 | TDP2 (0.51) | HSD17B1HSD17B2CYP3A4CYP2C9TTR | |
| SCHEMBL28937875 | 0.82 | L3MBTL1 (0.62) | CYP3A4CYP2C9TTRMAOAMAOB | |
| SCHEMBL16656217 | 0.78 | TTR (0.60) | CYP3A4TTRESR1ESR2MAOA | |
| SCHEMBL9843200 | 0.76 | MAPT (0.52) | CYP3A4MAOAMAOBMEN1MAPT | |
| SCHEMBL10936171 | 0.74 | MEN1 (0.60) | HSD17B1TTRESR1ESR2MAOA | |
| SCHEMBL28382691 | 0.74 | MAPT (0.42) | CYP3A4CYP2C9TTRMAOAMAOB | |
| SCHEMBL16601841 | 0.74 | MAOA (0.56) | CYP3A4ESR1ESR2MAOAMAOB | |
| SCHEMBL2770797 | 0.73 | MAOA (0.68) | CYP3A4TTRESR1ESR2MAOA | |
| SCHEMBL2770562 | 0.73 | MAOA (0.68) | CYP3A4TTRESR1ESR2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9383663-B2 | Electrophotographic photosensitive member, method of producing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2016-07-05 | — | — | US | disclosed |
| US-9383663-B2 | Electrophotographic photosensitive member, method of producing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2016-07-05 | — | — | US | disclosed |
| US-20140154620-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2014-06-05 | — | — | US | disclosed |
| US-20140154620-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2014-06-05 | — | — | US | disclosed |