Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 9/20 | 0.36 |
| ▸ | MMP9 | P14780 | 9/20 | 0.36 |
| ▸ | MMP8 | P22894 | 5/20 | 0.36 |
| ▸ | MMP12 | P39900 | 5/20 | 0.36 |
| ▸ | MMP14 | P50281 | 5/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.34 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15764781 | 0.82 | FOLH1 (0.44) | ALDH1A1FOLH1RIMKLANAALAD2 | |
| SCHEMBL25357016 | 0.77 | ALOX15 (0.64) | ALDH1A1KMT2AALOX15BLMPMP22 | |
| SCHEMBL25357021 | 0.77 | ALOX15 (0.64) | ALDH1A1KMT2AALOX15BLMPMP22 | |
| SCHEMBL29300242 | 0.75 | FOLH1 (0.40) | ALDH1A1MMP2MMP9MMP8MMP12 | |
| SCHEMBL28525595 | 0.73 | KMT2A (0.40) | KMT2AALOX15BLMPMP22MMP2 | |
| SCHEMBL30962435 | 0.72 | FOLH1 (0.61) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL12964947 | 0.71 | ALB (0.55) | NOD1FOLH1 | |
| SCHEMBL149082 | 0.71 | KMT2A (0.48) | KMT2AALOX15BLMPMP22MMP2 | |
| SCHEMBL29021876 | 0.70 | FOLH1 (0.56) | ALOX15BLMNOD1FOLH1RIMKLA | |
| SCHEMBL28089215 | 0.70 | C3AR1 (0.47) | KMT2ANOD1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014085575-A1 | METHODS FOR TREATING CANCER USING COMBINATION THERAPIES | ENDOCYTE, INC. (US) | 2014-06-05 | — | — | WO | disclosed |