Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 1/20 | 0.47 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.36 |
| ▸ | OTC | P00480 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.34 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | GNPAT | O15228 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30418562 | 0.86 | ALOX15 (0.37) | C3AR1FOLH1OTCMEN1KMT2A | |
| SCHEMBL5497852 | 0.83 | C3AR1 (0.55) | C3AR1SHMT1CTDSP1FOLH1MEN1 | |
| SCHEMBL27743728 | 0.83 | C3AR1 (0.51) | C3AR1SHMT1CTDSP1FOLH1OTC | |
| SCHEMBL2993887 | 0.83 | C3AR1 (0.51) | C3AR1SHMT1CTDSP1FOLH1OTC | |
| SCHEMBL5497855 | 0.83 | C3AR1 (0.55) | C3AR1SHMT1CTDSP1FOLH1MEN1 | |
| SCHEMBL29429369 | 0.83 | GNPAT (0.49) | C3AR1SHMT1CTDSP1FOLH1OTC | |
| SCHEMBL93363 | 0.81 | C3AR1 (0.47) | C3AR1SHMT1CTDSP1FOLH1OTC | |
| SCHEMBL30404095 | 0.81 | C3AR1 (0.47) | C3AR1SHMT1CTDSP1FOLH1OTC | |
| SCHEMBL143455 | 0.81 | C3AR1 (0.50) | C3AR1SHMT1CTDSP1FOLH1OTC | |
| SCHEMBL93364 | 0.81 | C3AR1 (0.47) | C3AR1SHMT1CTDSP1FOLH1OTC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279110-A | Heterocyclic compound, medicine containing described compound and application thereof and its preparation method | 勃林格殷格翰国际有限公司 | 2017-01-04 | — | — | CN | disclosed |
| CN-106163553-A | The compositions of multimeric multi-epitope influenza polypeptide and generation thereof | 彼昂德瓦克斯医药有限公司 | 2016-11-23 | — | — | CN | disclosed |
| CN-104024244-B | Heterocyclic compounds, medicaments containing said compounds, their use and processes for their preparation | 勃林格殷格翰国际有限公司 | 2016-09-14 | — | — | CN | disclosed |