Amiloxate

Amiloxate

SCHEMBL15765

COc1ccc(C=CC(=O)OCCC(C)C)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
SMN1; SMN2 Q16637 1/20 0.62
GSK3B P49841 1/20 0.56
F3 P13726 2/20 0.55
TAS1R3 Q7RTX0 3/20 0.54
TAS1R1 Q7RTX1 3/20 0.54
THRB P10828 1/20 0.54
ATM Q13315 1/20 0.54
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
MAPT P10636 1/20 0.52
CASP3 P42574 1/20 0.52
SENP7 Q9BQF6 1/20 0.52
SENP6 Q9GZR1 1/20 0.52
GAA P10253 1/20 0.52
HDAC3 O15379 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC2 Q92769 1/20 0.51
HDAC8 Q9BY41 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Amiloxate SCHEMBL15764 1.00 LMNA (1.00) LMNATDP1SMN1; SMN2GSK3BF3
Amiloxate SCHEMBL2228053 1.00 LMNA (1.00) LMNATDP1SMN1; SMN2GSK3BF3
Amiloxate SCHEMBL8095776 1.00 LMNA (1.00) LMNATDP1SMN1; SMN2GSK3BF3
Amiloxate SCHEMBL2228049 1.00 LMNA (1.00) LMNATDP1SMN1; SMN2GSK3BF3
Amiloxate SCHEMBL31304727 0.99 LMNA (0.97) LMNATDP1SMN1; SMN2GSK3BF3
Amiloxate SCHEMBL1768923 0.95 LMNA (0.90) LMNATDP1SMN1; SMN2GSK3BF3
Amiloxate SCHEMBL3136516 0.94 LMNA (0.88) LMNATDP1SMN1; SMN2GSK3BF3
SCHEMBL4907879 0.89 LMNA (0.81) LMNATDP1SMN1; SMN2GSK3BF3
SCHEMBL27795975 0.89 LMNA (0.81) LMNATDP1SMN1; SMN2GSK3BF3
SCHEMBL25221843 0.89 TDP1 (0.80) LMNATDP1SMN1; SMN2GSK3BTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14103 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075332-A Composition, preparation method thereof and sun-screening composition 2026-05-26 CN claimed
CN-122036500-A Preparation method of alkyl p-methoxy cinnamate 武汉能迈科香料有限公司 2026-05-15 CN claimed
CN-122031293-A Efficient waterproof and sun-proof synergistic composition suitable for oil-in-water type and application thereof 诺斯贝尔化妆品股份有限公司 2026-05-15 CN claimed
WO-2026099270-A1 BIODEGRADABLE UV ABSORBERS AND USES THEREOF II BASF SE (DE) 2026-05-15 WO claimed
WO-2026099732-A1 COSMETIC PRODUCTS WITH SOLAR PROTECTION COMPRISING POROUS POWDERS COATED WITH LIPOPHILIC AGENTS WITH SPF BOOSTER EFFECT INTERCOS S.P.A. (IT) 2026-05-15 WO claimed
US-20260130837-A1 SPF BOOSTER AND SUNCARE FORMULATIONS INCLUDING SAME DOW SILICONES CORP (US) 2026-05-14 US claimed
EP-3600224-B1 SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2026-05-06 EP claimed
WO-2026089857-A1 METHOD OF PREPARING AND USING A SKIN CARE COMPOSITION DOW SILICONES CORPORATION (US) 2026-04-30 WO claimed
WO-2026089856-A1 METHOD OF PREPARING AND USING A SKIN CARE FORMULATION DOW SILICONES CORPORATION (US) 2026-04-30 WO claimed
US-20260108435-A1 SUNSCREEN COMPOSITION WITH FUNCTIONALIZED ZEOLITE SPF BOOSTERS SAES GETTERS S.P.A. (IT) 2026-04-23 US claimed
US-5455048-A Sun filter microcapsules ROUSSEL UCLAF (FR) 1995-10-03 US claimed
EP-0669124-A1 Ultraviolet radiation absorbing composition ROHM AND HAAS COMPANY (US) 1995-08-30 EP claimed
EP-0419164-B1 Hair conditioning composition UNILEVER PLC (GB) 1994-11-30 EP claimed
EP-0386898-B1 SHAMPOO COMPOSITION UNILEVER PLC (GB) 1993-09-01 EP claimed
US-5186928-A Anionic surfactant, water-insoluble sunscreen, and cationic derivative of polygalactomannan gum CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1993-02-16 US claimed
EP-0509904-A1 Microencapsulation of sunscreen products, their preparation process, cosmetic and pharmaceutical compositions containing said microcapsules and their applications ROUSSEL UCLAF (FR) 1992-10-21 EP claimed
EP-0419164-A1 Hair conditioning composition UNILEVER PLC (GB) 1991-03-27 EP claimed
EP-0386898-A1 Shampoo composition UNILEVER PLC (GB) 1990-09-12 EP claimed
US-4284621-A SUNSCREEN FOR SKIN BAYER AKTIENGESELLSCHAFT (DE) 1981-08-18 US claimed
EP-0005182-B1 COMPOSITION AGAINST THE ACTION OF LIGHT BAYER AG (DE) 1981-07-29 EP claimed