Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.88 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.88 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | F3 | P13726 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25221843 | 0.95 | TDP1 (0.80) | LMNATDP1SMN1; SMN2CA12AKR1B10 | |
| Amiloxate SCHEMBL2228049 | 0.94 | LMNA (1.00) | LMNATDP1SMN1; SMN2GSK3BTAS1R3 | |
| Amiloxate SCHEMBL2228053 | 0.94 | LMNA (1.00) | LMNATDP1SMN1; SMN2GSK3BTAS1R3 | |
| Amiloxate SCHEMBL8095776 | 0.94 | LMNA (1.00) | LMNATDP1SMN1; SMN2GSK3BTAS1R3 | |
| Amiloxate SCHEMBL15764 | 0.94 | LMNA (1.00) | LMNATDP1SMN1; SMN2GSK3BTAS1R3 | |
| Amiloxate SCHEMBL15765 | 0.94 | LMNA (1.00) | LMNATDP1SMN1; SMN2GSK3BTAS1R3 | |
| Amiloxate SCHEMBL31304727 | 0.92 | LMNA (0.97) | LMNATDP1SMN1; SMN2GSK3BTAS1R3 | |
| Amiloxate SCHEMBL1768923 | 0.89 | LMNA (0.90) | LMNATDP1SMN1; SMN2GSK3BTAS1R3 | |
| SCHEMBL20943451 | 0.89 | LMNA (0.68) | LMNATDP1SMN1; SMN2CA12AKR1B10 | |
| SCHEMBL15838 | 0.87 | CA12 (0.71) | LMNATDP1SMN1; SMN2CA12AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2174644-B1 | Cosmetic composition comprising a dibenzoylmethane derivative and a dithiolane; Photostabilization of a dibenzoylmethane derivative | OREAL (FR) | 2012-11-14 | — | — | EP | disclosed |
| EP-2174644-A1 | Cosmetic composition comprising a dibenzoylmethane derivative and a dithiolane; Photostabilization of a dibenzoylmethane derivative | L'OREAL (FR) | 2010-04-14 | — | — | EP | disclosed |