Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | F3 | P13726 | 2/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amiloxate SCHEMBL15764 | 1.00 | LMNA (1.00) | LMNATDP1SMN1; SMN2GSK3BF3 | |
| Amiloxate SCHEMBL2228053 | 1.00 | LMNA (1.00) | LMNATDP1SMN1; SMN2GSK3BF3 | |
| Amiloxate SCHEMBL15765 | 1.00 | LMNA (1.00) | LMNATDP1SMN1; SMN2GSK3BF3 | |
| Amiloxate SCHEMBL2228049 | 1.00 | LMNA (1.00) | LMNATDP1SMN1; SMN2GSK3BF3 | |
| Amiloxate SCHEMBL31304727 | 0.99 | LMNA (0.97) | LMNATDP1SMN1; SMN2GSK3BF3 | |
| Amiloxate SCHEMBL1768923 | 0.95 | LMNA (0.90) | LMNATDP1SMN1; SMN2GSK3BF3 | |
| Amiloxate SCHEMBL3136516 | 0.94 | LMNA (0.88) | LMNATDP1SMN1; SMN2GSK3BF3 | |
| SCHEMBL4907879 | 0.89 | LMNA (0.81) | LMNATDP1SMN1; SMN2GSK3BF3 | |
| SCHEMBL27795975 | 0.89 | LMNA (0.81) | LMNATDP1SMN1; SMN2GSK3BF3 | |
| SCHEMBL25221843 | 0.89 | TDP1 (0.80) | LMNATDP1SMN1; SMN2GSK3BTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170095412-A1 | USE OF GLYCYRRHETIC ACID AND/OR GLYCYRRHIZIN FOR PRODUCING COSMETIC PREPARATIONS FOR TANNING THE SKIN | BEIERSDORF AG (DE) | 2017-04-06 | — | — | US | disclosed |
| US-6143906-A | REACTING ASCORBIC ACID OR ASCORBIC ACID DERIVATIVES WITH SORBIC ACID OR SORBIC ACID DERIVATIVE TO FORM ASCORBYL SORBATES WHICH IS USED AS COSMETIC OR DURG | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170095412-A1 | USE OF GLYCYRRHETIC ACID AND/OR GLYCYRRHIZIN FOR PRODUCING COSMETIC PREPARATIONS FOR TANNING THE SKIN | CUTA, TYR, AGER | LMNA 2645/4885TDP1 1591/4885SMN1; SMN2 4763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.