SCHEMBL1576548

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1575232	0.89	NPC1 (0.51)	RAB9ANPC1TAS1R3TAS1R1TAS1R2
	SCHEMBL1574631	0.86	MAPT (0.46)	RAB9ANPC1GRIN2BTSHRMAPT
	SCHEMBL1574671	0.86	ALOX5 (0.54)	RAB9ANPC1TAS1R3TAS1R1TAS1R2
	SCHEMBL1574821	0.86	KMT2A (0.51)	RAB9ANPC1GRIN2BMAPTPAX8
	SCHEMBL1575584	0.86	GRIN2B (0.51)	RAB9ANPC1GRIN2BFAAHMAPT
	SCHEMBL1574617	0.86	NPC1 (0.54)	RAB9ANPC1TAS1R3TAS1R1TAS1R2
	SCHEMBL1574531	0.86	MAPT (0.58)	RAB9ANPC1TAS1R3TAS1R1TAS1R2
	SCHEMBL1574442	0.86	NPC1 (0.52)	RAB9ANPC1FAAHMAPTSMN1; SMN2
	SCHEMBL1575130	0.86	NPC1 (0.54)	RAB9ANPC1TSHRMAPTSMN1; SMN2
	SCHEMBL1574656	0.85	ALDH1A1 (0.56)	RAB9AGRIN2BFAAHMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.