Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.35 |
| ▸ | ARG2 | P78540 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 3/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | BHMT | Q93088 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21955443 | 0.88 | ARG1 (0.36) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL16087209 | 0.84 | CYP2D6 (0.48) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL8211206 | 0.84 | CYP2D6 (0.48) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL18788686 | 0.81 | ARG1 (0.53) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL8022170 | 0.76 | — | — | |
| SCHEMBL11114575 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL11113277 | 0.74 | NOS2 (0.38) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL9200531 | 0.74 | NOS2 (0.35) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL4922553 | 0.74 | NOS2 (0.35) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL4922558 | 0.74 | NOS2 (0.35) | ARG1ARG2NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014083505-A1 | METHODS FOR MAKING CONJUGATES FROM DISULFIDE-CONTAINING PROTEINS | NOVARTIS AG (CH) | 2014-06-05 | — | — | WO | disclosed |