Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | BHMT | Q93088 | 5/20 | 0.47 |
| ▸ | ARG1 | P05089 | 1/20 | 0.38 |
| ▸ | ARG2 | P78540 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 4/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16087209 | 1.00 | CYP2D6 (0.48) | CYP2D6HIF1ABHMTARG1ARG2 | |
| SCHEMBL21955443 | 0.86 | ARG1 (0.36) | BHMTARG1ARG2CYP2C19NOS2 | |
| Carbocysteine SCHEMBL20854 | 0.84 | BHMT (0.59) | CYP2D6HIF1ABHMTARG1ARG2 | |
| SCHEMBL15765931 | 0.84 | ARG1 (0.35) | BHMTARG1ARG2NOS2NOS1 | |
| Carbocysteine SCHEMBL69149 | 0.84 | BHMT (0.59) | CYP2D6HIF1ABHMTARG1ARG2 | |
| Carbocysteine SCHEMBL6762355 | 0.84 | BHMT (0.59) | CYP2D6HIF1ABHMTARG1ARG2 | |
| Carbocysteine SCHEMBL9236855 | 0.84 | BHMT (0.59) | CYP2D6HIF1ABHMTARG1ARG2 | |
| Carbocysteine SCHEMBL15545269 | 0.82 | BHMT (0.57) | CYP2D6HIF1ABHMTARG1ARG2 | |
| Carbocysteine SCHEMBL19614507 | 0.82 | BHMT (0.57) | CYP2D6HIF1ABHMTARG1ARG2 | |
| Carbocysteine SCHEMBL15546452 | 0.82 | BHMT (0.57) | CYP2D6HIF1ABHMTARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398483-B1 | OXYNTOMODULIN ANALOGS | MERCK SHARP & DOHME (US) | 2014-09-24 | — | — | EP | disclosed |
| US-6086881-A | FOR USE AS AN IMMUNOGEN OR VACCINE; COMPRISING HAPTENS OR ANTIGENS FROM CHOSEN INFECTIOUS AGENT, AND CHEMICALLY SUBSTITUTED METALLIC OXIDE NANOPARTICLES COUPLED VIA THIOETHER BOND TO THE HAPTENS OR ANTIGENS | CHILDREN'S MEDICAL CENTER CORP. (US) | 2000-07-11 | — | — | US | disclosed |