Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.54 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.54 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15766030 | 0.89 | CA2 (0.54) | LMNAGAACA2CA1MEN1 | |
| SCHEMBL15766067 | 0.87 | TGM2 (0.59) | LMNAGAACA2CA1MEN1 | |
| SCHEMBL15766188 | 0.78 | CA2 (0.65) | LMNACA2CA1MEN1KMT2A | |
| SCHEMBL15766133 | 0.77 | KDR (0.59) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL15766059 | 0.74 | CA2 (0.70) | LMNAGAACA2CA1MEN1 | |
| SCHEMBL31196722 | 0.72 | SMN1; SMN2 (0.70) | LMNAGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15768048 | 0.71 | TGM2 (0.76) | CA2CA1ALDH1A1 | |
| SCHEMBL25722471 | 0.71 | MAPK1 (0.57) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6857070 | 0.69 | POLB (0.74) | MEN1KMT2ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL15766159 | 0.68 | POLB (0.66) | CA2MEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2740727-B1 | Quinazolinone analogues for use as anticonvulsant agents | UNIV KING SAUD (SA) | 2014-10-22 | — | — | EP | disclosed |
| EP-2740727-A1 | Quinazolinone analogues for use as anticonvulsant agents | King Saud University (SA) | 2014-06-11 | — | — | EP | disclosed |