Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | PNP | P00491 | 7/20 | 0.58 |
| ▸ | TGM2 | P21980 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15768048 | 0.87 | TGM2 (0.76) | KDRPNPTGM2ALDH1A1 | |
| SCHEMBL15766142 | 0.77 | LMNA (0.55) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15766030 | 0.74 | CA2 (0.54) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9671578 | 0.73 | PDE7A (0.76) | PDE7A | |
| SCHEMBL6034185 | 0.73 | TGM2 (1.00) | TGM2ALDH1A1LMNATDP1PDE7A | |
| SCHEMBL15766067 | 0.71 | TGM2 (0.59) | TGM2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15766188 | 0.71 | CA2 (0.65) | ALDH1A1LMNA | |
| SCHEMBL14010913 | 0.71 | TGM2 (0.75) | TGM2ALDH1A1LMNAPDE7ASMN1; SMN2 | |
| SCHEMBL15302024 | 0.70 | NPC1 (0.70) | LMNASMN1; SMN2 | |
| SCHEMBL18239988 | 0.70 | PDE7A (1.00) | TGM2ALDH1A1PDE7ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2740727-B1 | Quinazolinone analogues for use as anticonvulsant agents | UNIV KING SAUD (SA) | 2014-10-22 | — | — | EP | disclosed |
| EP-2740727-B1 | Quinazolinone analogues for use as anticonvulsant agents | UNIV KING SAUD (SA) | 2014-10-22 | — | — | EP | disclosed |
| EP-2740727-A1 | Quinazolinone analogues for use as anticonvulsant agents | King Saud University (SA) | 2014-06-11 | — | — | EP | disclosed |
| EP-2740727-A1 | Quinazolinone analogues for use as anticonvulsant agents | King Saud University (SA) | 2014-06-11 | — | — | EP | disclosed |