Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.81 |
| ▸ | ELANE | P08246 | 2/20 | 0.81 |
| ▸ | F7 | P08709 | 1/20 | 0.70 |
| ▸ | F3 | P13726 | 1/20 | 0.70 |
| ▸ | C1R | P00736 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 9/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | GUSB | P08236 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11812017 | 0.91 | MAPT (0.76) | MEN1KMT2AELANEF7F3 | |
| SCHEMBL31742428 | 0.90 | F7 (0.71) | MEN1KMT2AELANEF7F3 | |
| SCHEMBL31742427 | 0.90 | MEN1 (0.67) | MEN1KMT2AELANEF7F3 | |
| SCHEMBL692321 | 0.90 | KMT2A (1.00) | MEN1KMT2AELANEF7F3 | |
| SCHEMBL29633854 | 0.90 | KMT2A (1.00) | MEN1KMT2AELANEF7F3 | |
| SCHEMBL6567235 | 0.89 | MEN1 (0.72) | MEN1KMT2AELANEF7F3 | |
| SCHEMBL31742429 | 0.86 | MAPT (0.65) | MEN1KMT2AELANEF7F3 | |
| SCHEMBL31742426 | 0.84 | RAB9A (0.75) | MEN1KMT2AELANEF7F3 | |
| SCHEMBL913997 | 0.83 | KMT2A (0.67) | MEN1KMT2AELANEF7F3 | |
| SCHEMBL31742425 | 0.83 | MEN1 (0.64) | MEN1KMT2AELANEF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148368-B2 | 7-nitro-2-(3-nitro phenyl)-4H-3,1-benzoxazin-4-one or derivatives thereof for treating or preventing antiviral infections | RIAZUDDIN SHAIKH (PK) | 2012-04-03 | — | — | US | claimed |
| US-20120058080-A1 | 7-Nitro-2-(3-nitro phenyl)-4H-3,1-benzoxazin-4-one or derivatives thereof for treating or preventing antiviral infections | RIAZUDDIN SHAIKH (PK) | 2012-03-08 | — | — | US | claimed |
| US-8148368-B2 | 7-nitro-2-(3-nitro phenyl)-4H-3,1-benzoxazin-4-one or derivatives thereof for treating or preventing antiviral infections | RIAZUDDIN SHAIKH (PK) | 2012-04-03 | — | — | US | disclosed |
| US-8148368-B2 | 7-nitro-2-(3-nitro phenyl)-4H-3,1-benzoxazin-4-one or derivatives thereof for treating or preventing antiviral infections | RIAZUDDIN SHAIKH (PK) | 2012-04-03 | — | — | US | disclosed |
| US-20120058080-A1 | 7-Nitro-2-(3-nitro phenyl)-4H-3,1-benzoxazin-4-one or derivatives thereof for treating or preventing antiviral infections | RIAZUDDIN SHAIKH (PK) | 2012-03-08 | — | — | US | disclosed |
| US-20120058080-A1 | 7-Nitro-2-(3-nitro phenyl)-4H-3,1-benzoxazin-4-one or derivatives thereof for treating or preventing antiviral infections | RIAZUDDIN SHAIKH (PK) | 2012-03-08 | — | — | US | disclosed |