Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 8/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | F7 | P08709 | 1/20 | 0.61 |
| ▸ | F3 | P13726 | 1/20 | 0.61 |
| ▸ | C1R | P00736 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 7/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | ELANE | P08246 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.49 |
| ▸ | GABRD | O14764 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6567235 | 0.93 | MEN1 (0.72) | MEN1KMT2AMAPTL3MBTL1RAB9A | |
| SCHEMBL31742426 | 0.88 | RAB9A (0.75) | MEN1KMT2AMAPTL3MBTL1RAB9A | |
| SCHEMBL11812017 | 0.87 | MAPT (0.76) | MEN1KMT2AMAPTL3MBTL1RAB9A | |
| SCHEMBL6170277 | 0.84 | MEN1 (0.60) | MEN1KMT2AMAPTL3MBTL1RAB9A | |
| SCHEMBL157666 | 0.83 | MEN1 (0.81) | MEN1KMT2AMAPTL3MBTL1RAB9A | |
| SCHEMBL4146732 | 0.83 | RAB9A (0.76) | MEN1KMT2AMAPTL3MBTL1RAB9A | |
| SCHEMBL31742429 | 0.82 | MAPT (0.65) | MEN1KMT2AMAPTL3MBTL1RAB9A | |
| SCHEMBL6563905 | 0.82 | RAB9A (0.78) | MEN1KMT2AMAPTL3MBTL1RAB9A | |
| SCHEMBL914201 | 0.82 | MEN1 (0.68) | MEN1KMT2AMAPTL3MBTL1RAB9A | |
| SCHEMBL4153246 | 0.80 | RAB9A (0.75) | MEN1KMT2AMAPTL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250375454-A1 | METHODS FOR TREATING HEPATOCELLULAR CARCINOMA | UNIV HONG KONG POLYTECHNIC | 2025-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250375454-A1 | METHODS FOR TREATING HEPATOCELLULAR CARCINOMA | MYC, BCL2, MYCBP | MEN1 4101/4885KMT2A 2400/4885MAPT 4223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.