Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.61 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.57 |
| ▸ | THRA | P10827 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27914875 | 0.95 | KMT2A (0.57) | SMPD1PLA2G4BTHRATHRBKMT2A | |
| SCHEMBL17961060 | 0.93 | SMPD1 (0.68) | SMPD1PLA2G4BTHRATHRBKMT2A | |
| SCHEMBL17961074 | 0.93 | SMPD1 (0.68) | SMPD1PLA2G4BTHRATHRBKMT2A | |
| SCHEMBL17961053 | 0.93 | SMPD1 (0.68) | SMPD1PLA2G4BTHRATHRBKMT2A | |
| SCHEMBL11347541 | 0.92 | SMPD1 (0.67) | SMPD1PLA2G4BTHRATHRBKMT2A | |
| SCHEMBL17961066 | 0.92 | SMPD1 (0.66) | SMPD1PLA2G4BTHRATHRBKMT2A | |
| SCHEMBL23627035 | 0.89 | SMPD1 (0.67) | SMPD1PLA2G4BTHRATHRBKMT2A | |
| SCHEMBL17961071 | 0.88 | KMT2A (0.60) | SMPD1PLA2G4BTHRATHRBKMT2A | |
| SCHEMBL22438949 | 0.87 | SMPD1 (0.67) | SMPD1PLA2G4BTHRATHRBKMT2A | |
| SCHEMBL15766529 | 0.87 | SMPD1 (0.67) | SMPD1PLA2G4BTHRATHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2740724-B1 | COMPOUND FOR TREATING CARTILAGE DISORDERS | ONO PHARMACEUTICAL CO (JP) | 2016-12-28 | — | — | EP | disclosed |
| US-9085523-B2 | Compound for treating cartilage disorders | ONO PHARMACEUTICAL CO., LTD. (JP) | 2015-07-21 | — | — | US | disclosed |
| US-20140171388-A1 | COMPOUND FOR TREATING CARTILAGE DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2014-06-19 | — | — | US | disclosed |
| EP-2740724-A1 | COMPOUND FOR TREATING CARTILAGE DISORDERS | ONO Pharmaceutical Co., Ltd. (JP) | 2014-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140171388-A1 | COMPOUND FOR TREATING CARTILAGE DISORDERS | COL2A1, COL1A1, ADAMTS1 | SMPD1 4318/4885PLA2G4B 3569/4885THRA 714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.