Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15781198 | 1.00 | LMNA (0.43) | LMNAPKMALPIPTGS1XIAP | |
| SCHEMBL29013199 | 0.77 | LMNA (0.37) | LMNAPKMALPIPTGS1XIAP | |
| SCHEMBL6965136 | 0.76 | LMNA (0.46) | LMNAPKMCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL11398851 | 0.76 | SIRT1 (0.37) | LMNAPKMHSD17B10SMN1; SMN2MAPK1 | |
| SCHEMBL14574452 | 0.75 | DPP4 (0.48) | LMNAPKMSMN1; SMN2CYP2D6SRC | |
| SCHEMBL18135259 | 0.75 | LMNA (0.42) | LMNAPKMSLC7A5CYP2C9CYP2C19 | |
| SCHEMBL13845009 | 0.75 | DPP4 (0.48) | LMNAPKMSMN1; SMN2CYP2D6SRC | |
| SCHEMBL2033890 | 0.75 | LMNA (0.42) | LMNAPKMSLC7A5CYP2C9CYP2C19 | |
| SCHEMBL4552643 | 0.74 | LMNA (0.44) | LMNAPKMCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL74368 | 0.74 | LMNA (0.44) | LMNAPKMCYP2C9CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3187488-B1 | NOVEL AMINO-PHENYL-SULFONYL-ACETATE DERIVATIVE AND USE THEREOF | CJ HEALTHCARE CORP (KR) | 2020-02-19 | — | — | EP | disclosed |
| US-9556469-B2 | Method for classifying the presence or absence of a microorganism in a biological medium | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-01-31 | — | — | US | disclosed |
| US-20140162301-A1 | Method for Classifying the Presence or Absence of a Microorganism in a Biological Medium | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-06-12 | — | — | US | disclosed |