SCHEMBL15768586

SCHEMBL15768586

CC1=C(C)CC(C#N)CC1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17106304 1.00 CYP1A2 (0.34) CYP1A2CYP11B1CYP11B2
SCHEMBL17106303 1.00 CYP1A2 (0.34) CYP1A2CYP11B1CYP11B2
SCHEMBL17257515 0.69 KCNH2 (0.30)
SCHEMBL17257514 0.69 KCNH2 (0.30)
SCHEMBL19951605 0.68
SCHEMBL16620973 0.68
SCHEMBL16620975 0.68
SCHEMBL13562195 0.67 MEN1 (0.33)
SCHEMBL9845669 0.67 KDM4E (0.32) CYP1A2CYP11B1CYP11B2
SCHEMBL23294589 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3521409-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2024-08-14 EP disclosed
EP-3521409-A2 PERFUME SYSTEMS The Procter & Gamble Company (US) 2019-08-07 EP disclosed
EP-3122847-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2019-05-15 EP disclosed
EP-3122847-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2019-05-15 EP disclosed
EP-2928996-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2018-04-11 EP disclosed
EP-2928996-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2018-04-11 EP disclosed
EP-3122847-A1 PERFUME SYSTEMS The Procter & Gamble Company (US) 2017-02-01 EP disclosed
EP-2928997-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2017-01-25 EP disclosed
EP-2928997-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2017-01-25 EP disclosed
US-20160289593-A1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2016-10-06 US disclosed
US-20150267143-A1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2015-09-24 US disclosed
US-20150267143-A1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2015-09-24 US disclosed
US-20140161741-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 2014-06-12 US disclosed
US-20140161740-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 2014-06-12 US disclosed
US-20140161740-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 2014-06-12 US disclosed
US-20140161741-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 2014-06-12 US disclosed
WO-2014089253-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 2014-06-12 WO disclosed
WO-2014089254-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 2014-06-12 WO disclosed
WO-2014089253-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 2014-06-12 WO disclosed
WO-2014089254-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 2014-06-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160289593-A1 PERFUME SYSTEMS TRPA1, PORCN, PLIN5 CYP1A2 300/4885CYP11B1 2958/4885CYP11B2 2463/4885
US-20150267143-A1 PERFUME SYSTEMS TRPA1, PORCN, PLIN5 CYP1A2 300/4885CYP11B1 2958/4885CYP11B2 2463/4885
US-20140161741-A1 PERFUME SYSTEMS TRPA1, PORCN, PLIN5 CYP1A2 300/4885CYP11B1 2958/4885CYP11B2 2463/4885
US-20140161740-A1 PERFUME SYSTEMS TRPA1, PORCN, PLIN5 CYP1A2 300/4885CYP11B1 2958/4885CYP11B2 2463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.