SCHEMBL157689

SCHEMBL157689

O=C(COP(=O)(O)O)C(O)O

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TPI1 P60174 2/20 0.48
PGK1 P00558 1/20 0.46
PGK2 P07205 1/20 0.46
PGD P52209 3/20 0.43
MPI P34949 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8984258 0.79 PGK1 (0.47) TPI1PGK1PGK2PGDMPI
SCHEMBL8984257 0.79 PGK1 (0.47) TPI1PGK1PGK2PGDMPI
SCHEMBL8847394 0.79 PGK1 (0.47) TPI1PGK1PGK2PGDMPI
SCHEMBL7246853 0.79 PGK1 (0.33) TPI1PGK1PGK2PGD
SCHEMBL9558848 0.78 TPI1 (0.46) TPI1PGK1PGK2PGDMPI
SCHEMBL25391403 0.78 PGD (0.42) TPI1PGK1PGK2PGDMPI
SCHEMBL9100779 0.78 PGD (0.42) TPI1PGK1PGK2PGDMPI
SCHEMBL29026255 0.78 TPI1 (0.42) TPI1PGK1PGK2PGDMPI
SCHEMBL2697987 0.76 PGK1 (0.43) TPI1PGK1PGK2PGDMPI
SCHEMBL20608201 0.76 PGD (0.46) TPI1PGK1PGK2PGDMPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030003551-A1 Method for producing dihydroxyacetone-3-phosphate DAICEL CHEMICAL INDUSTRIES, INC., A JAPANESE CORPORATION 2003-01-02 US claimed
US-6451566-B1 SIMPLE CATALYTIC REACTION OF DIHYDROXYACETONE WITH THE BACTERIAL CELLS TRANSFORMED WITH THE GENE ENCODING A DIHYDROXYACETONE KINASE OR THE DIHYDROXYACETONE KINASE PRODUCED BY SAID BACTERIUM. DAICEL CHEMICAL INDUSTRIES, INC. (JP) 2002-09-17 US claimed
EP-0974662-A1 PROCESS FOR PRODUCING DIHYDROXYACETONE 3-PHOSPHATE DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2000-01-26 EP claimed
US-5122454-A Enzymically reacting lecithin and cholesterol; measurement of glycerol-3-phosphate TOYO YOZO COMPANY, LTD. (JP) 1992-06-16 US claimed
US-4693971-A Highly sensitive enzyme assay method TOYO JOZO KABUSHIKI KAISHA (JP) 1987-09-15 US claimed
JP-59140900-A None JP disclosed
US-20250066825-A1 A METHOD FOR GENETIC MODIFICATION FOR HIGH GC CONTENT MICROORGANISMS Technische Universität München (DE) 2025-02-27 US disclosed
CN-118369434-A Method for genetically modifying high CG content microorganism 慕尼黑科技大学 2024-07-19 CN disclosed
EP-4202043-A1 A METHOD FOR GENETIC MODIFICATION FOR HIGH CG CONTENT MICROORGANISMS Technische Universität München (DE) 2023-06-28 EP disclosed
EP-2414505-B1 ENGINEERING THE PATHWAY FOR SUCCINATE PRODUCTION UNIV FLORIDA (US) 2019-05-22 EP disclosed
US-10287611-B2 Engineering the pathway for succinate production UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2019-05-14 US disclosed
US-20180148732-A1 METHODS OF MODIFYING OIL CONTENT IN PLANTS AND PLANTS PRODUCED THEREBY THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2018-05-31 US disclosed
EP-0171142-B1 METHODS FOR PRODUCING PROTEINS AND TRANSFORMED CELLS, AND DNA CONSTRUCTS FOR CORRECTING HOST CELL DEFICIENCIES AND THEIR PREPARATION AND USE ZymoGenetics, Inc. (US) 1992-07-08 EP disclosed
US-5122454-A Enzymically reacting lecithin and cholesterol; measurement of glycerol-3-phosphate TOYO YOZO COMPANY, LTD. (JP) 1992-06-16 US disclosed
US-4931373-A TRANSFORMING DEFICIENT HOST CELL; CULTURING WITH DNA MOLECULE COMPRISING YEAST GENE ZYMOGENETICS, INC. (US) 1990-06-05 US disclosed
US-4693971-A Highly sensitive enzyme assay method TOYO JOZO KABUSHIKI KAISHA (JP) 1987-09-15 US disclosed
US-4693971-A Highly sensitive enzyme assay method TOYO JOZO KABUSHIKI KAISHA (JP) 1987-09-15 US disclosed
EP-0171142-A1 Methods for producing proteins and transformed cells, and DNA constructs for correcting host cell deficiencies and their preparation and use ZymoGenetics, Inc. (US) 1986-02-12 EP disclosed
JP-S59140900-A NOVEL METHOD FOR HIGHLY SENSITIVE, ENZYMATIC DETERMINATION TOYO JOZO CO LTD 1984-08-13 JP disclosed
US-4275161-A CULTURING AEROCOCCUS BACTERIA TOYO JOZO KABUSHIKI KAISHA (JP) 1981-06-23 US disclosed