Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.52 |
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | PARP1 | P09874 | 4/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15568360 | 0.85 | CCNB2 (0.44) | KDM4CCDC7HPGDPARP1ALDH1A1 | |
| SCHEMBL22201443 | 0.81 | ALDH1A1 (0.59) | CDC7HPGDPARP1ALDH1A1KDM4E | |
| SCHEMBL828493 | 0.80 | TNKS (0.63) | HPGDPARP1ALDH1A1KDM4ENPC1 | |
| SCHEMBL29639160 | 0.80 | TNKS (0.63) | HPGDPARP1ALDH1A1KDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL6648959 | 0.79 | ALDH1A1 (0.61) | CDC7HPGDPARP1ALDH1A1KDM4E | |
| SCHEMBL15567849 | 0.79 | TNKS (0.47) | KDM4CPARP1TNKS | |
| SCHEMBL24746791 | 0.78 | CDC7 (0.45) | KDM4CCDC7HPGDPARP1ALDH1A1 | |
| SCHEMBL30064139 | 0.78 | CDC7 (0.45) | KDM4CCDC7HPGDPARP1ALDH1A1 | |
| SCHEMBL15568105 | 0.77 | PDE10A (0.51) | KDM4CTNKSMAPT | |
| SCHEMBL6492488 | 0.77 | CYP19A1 (0.63) | CDC7HPGDALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |