Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TNKS | O95271 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | CDC7 | O00311 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | APAF1 | O14727 | 2/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6648959 | 0.98 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ENPC1LMNA | |
| SCHEMBL29639160 | 0.86 | TNKS (0.63) | ALDH1A1HPGDKDM4ENPC1LMNA | |
| SCHEMBL828493 | 0.86 | TNKS (0.63) | ALDH1A1HPGDKDM4ENPC1LMNA | |
| SCHEMBL30064139 | 0.83 | CDC7 (0.45) | ALDH1A1HPGDKDM4ENPC1LMNA | |
| SCHEMBL24746791 | 0.83 | CDC7 (0.45) | ALDH1A1HPGDKDM4ENPC1LMNA | |
| SCHEMBL15775130 | 0.81 | KDM4C (0.52) | ALDH1A1HPGDKDM4ENPC1LMNA | |
| SCHEMBL4774571 | 0.80 | TNKS (0.61) | ALDH1A1HPGDKDM4ENPC1LMNA | |
| SCHEMBL30160913 | 0.80 | PARP1 (0.61) | ALDH1A1HPGDKDM4ENPC1LMNA | |
| SCHEMBL311943 | 0.80 | TNKS (0.61) | ALDH1A1HPGDKDM4ENPC1LMNA | |
| SCHEMBL30161077 | 0.80 | TNKS (0.65) | ALDH1A1HPGDKDM4ENPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |