Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | PPM1B | O75688 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1578042 | 1.00 | MAPT (0.39) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7189787 | 1.00 | MAPT (0.39) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1578216 | 1.00 | MAPT (0.39) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1577775 | 0.86 | PPM1B (0.39) | ALDH1A1LMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL3691417 | 0.85 | ALDH1A1 (0.47) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1577887 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LMNAL3MBTL1HPGD | |
| SCHEMBL16409442 | 0.83 | LMNA (0.41) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1578269 | 0.82 | EPHX2 (0.43) | — | |
| SCHEMBL8462991 | 0.82 | ALDH1A1 (0.40) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL18900188 | 0.82 | MAPT (0.38) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8409831-B2 | Method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-04-02 | — | — | US | disclosed |
| EP-2311974-B1 | PROCESS FOR PRODUCING (1S,2R)-2-CHLORO-2-FLUOROCYCLOPROPANECARBOXYLIC ACID | SUMITOMO CHEMICAL CO (JP) | 2012-12-19 | — | — | EP | disclosed |
| US-20110117616-A1 | METHOD FOR PRODUCING (1S,2R)-2-CHLORO-2-FLUOROCYCLOPROPANECARBOXYLIC ACID | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-05-19 | — | — | US | disclosed |
| EP-2311974-A1 | METHOD FOR PRODUCING (1S,2R)-2-CHLORO-2-FLUOROCYCLOPROPANECARBOXYLIC ACID | Sumitomo Chemical Company, Limited (JP) | 2011-04-20 | — | — | EP | disclosed |