Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1577998 | 0.90 | CA12 (0.47) | TRPC6 | |
| SCHEMBL1577740 | 0.89 | GPR119 (0.50) | GPR119 | |
| SCHEMBL1577769 | 0.89 | GPR119 (0.46) | GPR119EPHX2 | |
| SCHEMBL1577824 | 0.89 | NPY2R (0.42) | GPR119PRMT5NPY2RTRPC6 | |
| SCHEMBL14141973 | 0.88 | GPR119 (0.50) | GPR119PRMT5NPY2R | |
| SCHEMBL1577585 | 0.88 | EPHX2 (0.43) | GPR119PRMT5EPHX2 | |
| SCHEMBL1577745 | 0.87 | GPR119 (0.49) | GPR119 | |
| SCHEMBL1577926 | 0.87 | GPR119 (0.65) | GPR119 | |
| SCHEMBL1577838 | 0.87 | NPC1 (0.44) | GPR119PRMT5NPY2RTRPC6 | |
| SCHEMBL1577330 | 0.87 | GPR119 (0.51) | GPR119PRMT5NPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140018537-A1 | GPR119 AGONIST | NIPPON CHEMIPHAR CO., LTD. (JP) | 2014-01-16 | — | — | US | disclosed |
| US-8536176-B2 | GPR119 agonist | NIPPON CHEMIPHAR CO., LTD. (JP) | 2013-09-17 | — | — | US | disclosed |
| US-20110137032-A1 | GPR119 AGONIST | NIPPON CHEMIPHAR CO., LTD. (JP) | 2011-06-09 | — | — | US | disclosed |
| EP-2311822-A1 | GPR119 AGONIST | Nippon Chemiphar Co., Ltd. (JP) | 2011-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018537-A1 | GPR119 AGONIST | GPR119, GPR27, GPR52 | GPR119 1/4885PRMT5 839/4885NPY2R 55/4885 |
| US-20110137032-A1 | GPR119 AGONIST | GPR119, GPR27, GPR52 | GPR119 1/4885PRMT5 839/4885NPY2R 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.