Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5078529 | 1.00 | MAPK1 (0.38) | MAPK1MEN1KMT2ALMNACYP2C9 | |
| SCHEMBL1706674 | 0.83 | MAPK1 (0.40) | MAPK1MEN1KMT2ALMNACYP2C9 | |
| SCHEMBL5077796 | 0.78 | MAPK1 (0.37) | MAPK1MEN1KMT2ALMNACYP2C9 | |
| SCHEMBL1578050 | 0.77 | — | — | |
| SCHEMBL295935 | 0.77 | MAPK1 (0.41) | MAPK1MEN1KMT2AHRH3EPHX2 | |
| SCHEMBL3358594 | 0.77 | — | — | |
| SCHEMBL8466617 | 0.76 | DGAT1 (0.38) | MAPK1MEN1KMT2AEPHX2 | |
| SCHEMBL1577514 | 0.73 | MAPT (0.39) | MEN1KMT2ALMNACYP2C9 | |
| SCHEMBL1690170 | 0.73 | HRH3 (0.41) | MAPK1MEN1KMT2AHRH3EPHX2 | |
| SCHEMBL7189787 | 0.73 | MAPT (0.39) | MEN1KMT2ALMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8409831-B2 | Method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-04-02 | — | — | US | disclosed |
| EP-2311974-B1 | PROCESS FOR PRODUCING (1S,2R)-2-CHLORO-2-FLUOROCYCLOPROPANECARBOXYLIC ACID | SUMITOMO CHEMICAL CO (JP) | 2012-12-19 | — | — | EP | disclosed |
| US-20110117616-A1 | METHOD FOR PRODUCING (1S,2R)-2-CHLORO-2-FLUOROCYCLOPROPANECARBOXYLIC ACID | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-05-19 | — | — | US | disclosed |
| EP-2311974-A1 | METHOD FOR PRODUCING (1S,2R)-2-CHLORO-2-FLUOROCYCLOPROPANECARBOXYLIC ACID | Sumitomo Chemical Company, Limited (JP) | 2011-04-20 | — | — | EP | disclosed |