SCHEMBL15775443

SCHEMBL15775443

c1ccc2nc(-c3nccc4ccccc34)ccc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.49
NPC1 O15118 8/20 0.49
CYP3A4 P08684 4/20 0.49
AR P10275 4/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2D6 P10635 2/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
KDM4E B2RXH2 7/20 0.45
KMT2A Q03164 4/20 0.45
MAPT P10636 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
GLA P06280 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
CYP2A6 P11509 1/20 0.44
F12 P00748 1/20 0.44
PLAU P00749 1/20 0.44
NCF1 P14598 1/20 0.44
NOS3 P29474 1/20 0.44
NOS1 P29475 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29610252 1.00 RAB9A (0.49) RAB9ANPC1CYP3A4ARCYP1A2
SCHEMBL18890764 0.81 KDM4E (0.48) RAB9ANPC1CYP3A4CYP1A2KDM4E
SCHEMBL30412818 0.80 AR (0.39) RAB9ANPC1CYP3A4ARCYP1A2
SCHEMBL199273 0.78 PLAU (0.60) RAB9ANPC1CYP3A4CYP1A2CYP2C19
SCHEMBL29923403 0.78 PLAU (0.60) RAB9ANPC1CYP3A4CYP1A2CYP2C19
SCHEMBL4494824 0.77 RAB9A (0.53) RAB9ANPC1CYP3A4ARCYP1A2
SCHEMBL7471796 0.77 AR (0.36) RAB9ANPC1CYP3A4ARCYP1A2
SCHEMBL25461169 0.77 RAB9A (0.49) RAB9ANPC1CYP3A4ARCYP1A2
SCHEMBL30522769 0.76 PLAU (0.58) RAB9ANPC1CYP3A4CYP1A2CYP2C19
SCHEMBL31268563 0.76 HTR2C (0.43) RAB9ANPC1CYP3A4CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114695800-A TADF sensitized organic electroluminescent device and display device containing same 江苏三月科技股份有限公司 2022-07-01 CN disclosed
CN-111712495-A Hydroxy isoxazolines and derivatives thereof 拜耳公司 2020-09-25 CN disclosed
EP-3466932-A1 PRODUCTION METHOD FOR BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC COMPOUND Kobelco Eco-Solutions Co., Ltd (JP) 2019-04-10 EP disclosed
CN-109195953-A The manufacturing method of two ring type nitrogen-containing heterocycle compounds 株式会社神钢环境舒立净 2019-01-11 CN disclosed
WO-2014086851-A1 COMPOSITIONS COMPRISING A QUILLAY EXTRACT AND A FUNGICIDAL INHIBITOR OF RESPIRATORY COMPLEX III AT QO SITE BASF AGRO B.V., ARNHEM (NL) (CH) 2014-06-12 WO disclosed
WO-2014086850-A1 COMPOSITIONS COMPRISING A QUILLAY EXTRACT AND A FUNGICIDAL INHIBITOR OF RESPIRATORY COMPLEX II BASF AGRO B.V., ARNHEM (NL) (CH) 2014-06-12 WO disclosed
WO-2014086854-A1 COMPOSITIONS COMPRISING A QUILLAY EXTRACT AND A PLANT GROWTH REGULATOR BASF AGRO B.V., ARNHEM (NL) (CH) 2014-06-12 WO disclosed
CN-102869648-A Pyrazole synthesis by coupling of carboxylic acid derivatives and enamines WESTFAELISHE WILHELMS U MUENSTER 2013-01-09 CN disclosed