Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 7/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 7/20 | 0.42 |
| ▸ | PARP1 | P09874 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 2/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618963 | 0.92 | ALDH1A1 (0.56) | ALDH1A1GAAPOLBRXFP1MAPT | |
| SCHEMBL2823766 | 0.86 | ALDH1A1 (0.64) | ALDH1A1GAAPOLBRXFP1MAPT | |
| SCHEMBL15775502 | 0.84 | PARP1 (0.59) | ALDH1A1GAAPOLBRXFP1MAPT | |
| SCHEMBL15775687 | 0.84 | TNKS (0.59) | ALDH1A1GAAPOLBRXFP1MAPT | |
| SCHEMBL10628275 | 0.84 | ALDH1A1 (0.61) | ALDH1A1GAAPOLBRXFP1MAPT | |
| SCHEMBL8618978 | 0.84 | KDM4E (0.61) | ALDH1A1GAAPOLBRXFP1MAPT | |
| SCHEMBL8618923 | 0.84 | TNKS (0.59) | ALDH1A1GAAPOLBRXFP1MAPT | |
| SCHEMBL15775265 | 0.84 | MAPT (0.68) | ALDH1A1GAAPOLBRXFP1MAPT | |
| SCHEMBL6887071 | 0.82 | ALDH1A1 (0.52) | ALDH1A1GAAPOLBRXFP1MAPT | |
| SCHEMBL3461430 | 0.81 | ALDH1A1 (0.49) | ALDH1A1GAAPOLBRXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |