Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 4/20 | 0.56 |
| ▸ | TNKS | O95271 | 3/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618963 | 0.94 | ALDH1A1 (0.56) | ALDH1A1GAARXFP1POLBNPC1 | |
| SCHEMBL8620408 | 0.89 | NR1I3 (0.54) | ALDH1A1GAARXFP1POLBNPC1 | |
| SCHEMBL6887071 | 0.88 | ALDH1A1 (0.52) | ALDH1A1GAARXFP1POLBNPC1 | |
| SCHEMBL8618923 | 0.86 | TNKS (0.59) | ALDH1A1GAARXFP1POLBNPC1 | |
| SCHEMBL15775265 | 0.86 | MAPT (0.68) | ALDH1A1GAARXFP1POLBNPC1 | |
| SCHEMBL15775687 | 0.86 | TNKS (0.59) | ALDH1A1GAARXFP1POLBNPC1 | |
| SCHEMBL15775502 | 0.86 | PARP1 (0.59) | ALDH1A1GAARXFP1POLBPARP1 | |
| SCHEMBL8618978 | 0.86 | KDM4E (0.61) | ALDH1A1GAARXFP1POLBNPC1 | |
| SCHEMBL15775875 | 0.86 | ALDH1A1 (0.49) | ALDH1A1GAARXFP1POLBNPC1 | |
| SCHEMBL10628275 | 0.86 | ALDH1A1 (0.61) | ALDH1A1GAARXFP1POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563272-B | Preparation method of 2-phenylquinazolinone compound | 三峡大学 | 2023-03-10 | — | — | CN | claimed |
| CN-113563272-A | Preparation method of 2-phenylquinazolinone compound | 三峡大学 | 2021-10-29 | — | — | CN | claimed |
| CN-108033919-B | Method for synthesizing 2-phenyl quinazolinone compound by taking styrene compound as raw material | 温州大学 | 2021-03-02 | — | — | CN | claimed |
| CN-108129402-B | Method for synthesizing 2-phenyl quinazolinone compound by taking tolane compound as raw material | 温州大学 | 2021-02-12 | — | — | CN | claimed |
| US-6479499-B1 | INHIBITORS OF TUBULIN POLYMERIZATION | NATIONAL SCIENCE COUNCIL (TW) | 2002-11-12 | — | — | US | claimed |
| CN-115650924-B | Green synthesis method of quinazolinone | 山东华泰新材料技术研发有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-117169175-A | Method for detecting surface components of lithium metal negative electrode | 清华大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-116444444-A | Method for preparing 2-substituted quinazolinone compound | 盐城工业职业技术学院 | 2023-07-18 | — | — | CN | disclosed |
| CN-113563272-B | Preparation method of 2-phenylquinazolinone compound | 三峡大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-113563272-B | Preparation method of 2-phenylquinazolinone compound | 三峡大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-113563272-B | Preparation method of 2-phenylquinazolinone compound | 三峡大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-115650924-A | Green synthesis method of quinazolinone | 上海橡实化学有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-1476435-A | Fluorinated quinolones as antimitotic and antitumor agents | 北卡罗来纳查佩尔山大学 | 2004-02-18 | — | — | CN | disclosed |
| EP-1322615-A2 | FLUORINATED QUINOLONES AS ANTIMITOTIC AND ANTITUMOR AGENTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2003-07-02 | — | — | EP | disclosed |
| US-6569870-B1 | Anticarcinogenic agents for breast and ovarian cancer | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2003-05-27 | — | — | US | disclosed |
| US-6479499-B1 | INHIBITORS OF TUBULIN POLYMERIZATION | NATIONAL SCIENCE COUNCIL (TW) | 2002-11-12 | — | — | US | disclosed |
| US-6479499-B1 | INHIBITORS OF TUBULIN POLYMERIZATION | NATIONAL SCIENCE COUNCIL (TW) | 2002-11-12 | — | — | US | disclosed |
| WO-2002026730-A2 | FLUORINATED QUINOLONES AS ANTIMITOTIC AND ANTITUMOR AGENTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2002-04-04 | — | — | WO | disclosed |
| US-5728712-A | 3,4-disubstituted-phenylsulphonamides and their therapeutic use | CHIROSCIENCE LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |
| WO-1996036611-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |