Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TNKS | O95271 | 4/20 | 0.59 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.59 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.59 |
| ▸ | CTSV | O60911 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | SI | P14410 | 1/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618963 | 0.92 | ALDH1A1 (0.56) | KDM4ENPC1RAB9ASMN1; SMN2TNKS | |
| SCHEMBL2823766 | 0.86 | ALDH1A1 (0.64) | KDM4ENPC1RAB9ASMN1; SMN2TNKS | |
| SCHEMBL15775687 | 0.84 | TNKS (0.59) | KDM4ENPC1RAB9ASMN1; SMN2TNKS | |
| SCHEMBL15775502 | 0.84 | PARP1 (0.59) | TNKSTNKS2GAAMGAMSI | |
| SCHEMBL10628275 | 0.84 | ALDH1A1 (0.61) | KDM4ENPC1RAB9ASMN1; SMN2TNKS | |
| SCHEMBL15775265 | 0.84 | MAPT (0.68) | NPC1RAB9ATNKSTNKS2PARP2 | |
| SCHEMBL8618923 | 0.84 | TNKS (0.59) | KDM4ENPC1RAB9ASMN1; SMN2TNKS | |
| SCHEMBL15775875 | 0.84 | ALDH1A1 (0.49) | KDM4ENPC1RAB9ASMN1; SMN2TNKS | |
| SCHEMBL15775354 | 0.83 | TNKS (0.62) | TNKSTNKS2PARP2GAAMAPK14 | |
| SCHEMBL6887071 | 0.82 | ALDH1A1 (0.52) | KDM4ENPC1RAB9ASMN1; SMN2TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686560-A | TREATING A MONOMER WITH A BASE IN A DIPOLAR SOLVENT | HITACHI CHEMICAL CO., LTD. (JP) | 1997-11-11 | — | — | US | claimed |
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |
| US-5849861-A | Polyquinazolines and methods for their preparation | HITACHI CHEMICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| US-5686560-A | TREATING A MONOMER WITH A BASE IN A DIPOLAR SOLVENT | HITACHI CHEMICAL CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |