Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 12/20 | 0.48 |
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1577973 | 0.99 | HTR1A (0.48) | HTR1AHTR7HTR1D | |
| SCHEMBL1577843 | 0.86 | HTR1A (0.52) | HTR1AHTR7HTR1D | |
| Hydrochloric Acid SCHEMBL1577952 | 0.85 | HTR1A (0.51) | HTR1AHTR7HTR1D | |
| SCHEMBL1578095 | 0.84 | HTR1A (0.66) | HTR1AHTR7HTR1D | |
| Hydrochloric Acid SCHEMBL1578045 | 0.83 | HTR1A (0.65) | HTR1AHTR7HTR1D | |
| SCHEMBL15589874 | 0.82 | HTR1A (0.54) | HTR1AHTR7HTR1D | |
| Hydrochloric Acid SCHEMBL15589853 | 0.81 | HTR1A (0.53) | HTR1AHTR7HTR1D | |
| SCHEMBL1578041 | 0.80 | HTR1A (0.57) | HTR1AHTR7HTR1D | |
| SCHEMBL1578156 | 0.80 | HTR1A (0.47) | HTR1AHTR7HTR1D | |
| SCHEMBL1577923 | 0.80 | HTR1A (0.45) | HTR1AHTR7HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118263-A1 | BENZOTHIOPHENE ALKANOL PIPERAZINE DERIVATIVES AND THEIR USE AS ANTIDEPRESSANT | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO. LTD. (CN) | 2011-05-19 | — | — | US | claimed |
| EP-2311828-A1 | BENZOTHIOPHENE ALKANOL PIPERAZINE DERIVATIVES AND THEIR USE AS ANTIDEPRESSANT | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2011-04-20 | — | — | EP | claimed |
| US-20110118263-A1 | BENZOTHIOPHENE ALKANOL PIPERAZINE DERIVATIVES AND THEIR USE AS ANTIDEPRESSANT | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO. LTD. (CN) | 2011-05-19 | — | — | US | disclosed |
| EP-2311828-A1 | BENZOTHIOPHENE ALKANOL PIPERAZINE DERIVATIVES AND THEIR USE AS ANTIDEPRESSANT | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2011-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118263-A1 | BENZOTHIOPHENE ALKANOL PIPERAZINE DERIVATIVES AND THEIR USE AS ANTIDEPRESSANT | TPH1, HTR1A, TPH2 | HTR1A 2/4885HTR7 25/4885HTR1D 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.