Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | TBK1 | Q9UHD2 | 18/20 | 0.46 |
| ▸ | IKBKE | Q14164 | 11/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16075155 | 1.00 | SYK (0.49) | SYKTBK1IKBKE | |
| SCHEMBL16075158 | 1.00 | SYK (0.49) | SYKTBK1IKBKE | |
| SCHEMBL13723300 | 0.92 | SYK (0.58) | SYKTBK1IKBKE | |
| SCHEMBL16075152 | 0.88 | SYK (0.40) | SYKTBK1IKBKE | |
| SCHEMBL23876586 | 0.84 | SYK (0.43) | SYKTBK1IKBKE | |
| SCHEMBL17630232 | 0.83 | TBK1 (0.44) | TBK1IKBKE | |
| SCHEMBL22470577 | 0.83 | TBK1 (0.44) | TBK1IKBKE | |
| SCHEMBL15320475 | 0.83 | KDM4E (0.49) | TBK1IKBKE | |
| SCHEMBL15320480 | 0.83 | KDM4E (0.49) | TBK1IKBKE | |
| SCHEMBL15321446 | 0.83 | KDM4E (0.49) | TBK1IKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9597310-B2 | Indanyloxydihydrobenzofuranylacetic acids | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-03-21 | — | — | US | disclosed |
| US-20140163025-A1 | INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140163025-A1 | INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | GPR119, GPBAR1, GPR52 | SYK 4442/4885TBK1 4518/4885IKBKE 1449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.