Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10932269 | 0.81 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HPGDTBXAS1L3MBTL1 | |
| SCHEMBL14226876 | 0.81 | L3MBTL1 (0.70) | ALDH1A1HPGDMAOBL3MBTL1GAA | |
| SCHEMBL578734 | 0.81 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HPGDMAOBAOC3 | |
| SCHEMBL24627424 | 0.81 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2HPGDMAOBAOC3 | |
| SCHEMBL10460818 | 0.80 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2HPGDMAOBAOC3 | |
| SCHEMBL10754241 | 0.80 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2HPGDMAOBAOC3 | |
| SCHEMBL28258061 | 0.80 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL12503056 | 0.79 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2HPGDMAOBAOC3 | |
| SCHEMBL19287208 | 0.79 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2HPGDL3MBTL1GAA | |
| SCHEMBL7637707 | 0.79 | TP53 (0.66) | ALDH1A1SMN1; SMN2HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087110-A1 | METHOD FOR SYNTHESISING AN ADDITION SALT WITH A PHARMACEUTICALLY ACCEPTABLE ACID OF 4-{3-[CIS-HEXAHYDROCYCLOPENTA[C]PYRROL-2(1H)-YL]PROPOXY}BENZAMIDE, AND THE ASSOCIATED CRYSTALLINE FORMS | LES LABORATOIRES SERVIER (FR) | 2014-06-12 | — | — | WO | disclosed |