SCHEMBL15798371

SCHEMBL15798371

CCCCC(=O)CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)O

nearest known ligand 0.88

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NAA50 Q9GZZ1 2/20 0.84
▸ EP300 Q09472 3/20 0.81
▸ CHAT P28329 2/20 0.81
▸ AURKA O14965 2/20 0.81
▸ KAT5 Q92993 2/20 0.81
▸ KAT2B Q92831 1/20 0.81
▸ CREBBP Q92793 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29512275 0.99 NAA50 (0.83) NAA50EP300CHATAURKAKAT5
SCHEMBL22715872 0.99 NAA50 (0.83) NAA50EP300CHATAURKAKAT5
SCHEMBL1333244 0.98 NAA50 (0.84) NAA50EP300CHATAURKAKAT5
SCHEMBL30558687 0.98 NAA50 (0.84) NAA50EP300CHATAURKAKAT5
SCHEMBL25273107 0.98 NAA50 (0.83) NAA50EP300CHATAURKAKAT5
SCHEMBL1332729 0.98 NAA50 (0.83) NAA50EP300CHATAURKAKAT5
SCHEMBL11026148 0.98 NAA50 (0.83) NAA50EP300CHATAURKAKAT5
SCHEMBL2510648 0.98 NAA50 (0.83) NAA50EP300CHATAURKAKAT5
SCHEMBL31475488 0.98 NAA50 (0.83) NAA50EP300CHATAURKAKAT5
SCHEMBL380634 0.98 NAA50 (0.83) NAA50EP300CHATAURKAKAT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9790525-B2 Methods of producing 7-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage INVISTA NORTH AMERICA S.A.R.L. (US) 2017-10-17 — — US claimed
US-20180002729-A1 METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUNDS INVISTA NORTH AMERICA S.A.R.L. 2018-01-04 — — US disclosed
US-9790525-B2 Methods of producing 7-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage INVISTA NORTH AMERICA S.A.R.L. (US) 2017-10-17 — — US disclosed
US-9738914-B2 Methods, reagents and cells for biosynthesizing compounds INVISTA NORTH AMERICA S.A.R.L. (US) 2017-08-22 — — US disclosed
EP-3155109-A1 METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUNDS Invista Technologies S.A R.L. (CH) 2017-04-19 — — EP disclosed
WO-2015195678-A1 METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUNDS INVISTA TECHNOLOGIES S.À R.L. (CH) 2015-12-23 — — WO disclosed
US-20150361465-A1 METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUNDS INV NYLON CHEMICALS AMERICAS, LLC 2015-12-17 — — US disclosed
EP-2931907-A2 METHODS OF PRODUCING 7-CARBON CHEMICALS VIA CoA-DEPENDENT CARBON CHAIN ELONGATION ASSOCIATED WITH CARBON STORAGE Invista Technologies S.A R.L. (CH) 2015-10-21 — — EP disclosed
US-20140248673-A1 Methods of Producing 7-Carbon Chemicals via CoA-Dependent Carbon Chain Elongation Associated with Carbon Storage INVISTA North America S.á r.I. (US) 2014-09-04 — — US disclosed
WO-2014093847-A2 METHODS OF PRODUCING 7-CARBON CHEMICALS VIA CoA-DEPENDENT CARBON CHAIN ELONGATION ASSOCIATED WITH CARBON STORAGE INVISTA NORTH AMERICA S.A.R.L. (US) 2014-06-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150361465-A1 METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUNDS PNMT, HNMT, ACOT7 NAA50 212/4885EP300 886/4885CHAT 403/4885
US-20180002729-A1 METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUNDS PNMT, HNMT, ACOT7 NAA50 212/4885EP300 886/4885CHAT 403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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