SCHEMBL15801331

SCHEMBL15801331

Cc1ccc(Oc2c(F)c(F)c(-c3c(F)c(F)c(Oc4ccc(N)cc4)c(F)c3F)c(F)c2F)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TEAD4 Q15561 1/20 0.62
ALDH1A1 P00352 6/20 0.60
MAPT P10636 6/20 0.60
TDP1 Q9NUW8 3/20 0.60
POLB P06746 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.48
ACHE P22303 1/20 0.46
CYP3A4 P08684 1/20 0.45
TSHR P16473 1/20 0.45
HSP90AA1 P07900 1/20 0.43
ENPP3 O14638 1/20 0.43
ALPL P05186 1/20 0.43
XIAP P98170 1/20 0.43
MAOA P21397 2/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPK1 P28482 2/20 0.39
NPC1 O15118 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39
MAOB P27338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15801333 0.94 TEAD4 (0.69) TEAD4ALDH1A1MAPTTDP1POLB
SCHEMBL1334036 0.91 ALDH1A1 (0.54) TEAD4ALDH1A1MAPTTDP1POLB
SCHEMBL1656495 0.84 ALDH1A1 (0.62) TEAD4ALDH1A1MAPTTDP1POLB
SCHEMBL30681849 0.81 ALDH1A1 (0.48) TEAD4ALDH1A1MAPTTDP1POLB
SCHEMBL19360416 0.79 TSHR (0.36) TEAD4ALDH1A1MAPTTDP1POLB
SCHEMBL4569587 0.79 TEAD4 (0.45) TEAD4ALDH1A1MAPTTDP1POLB
SCHEMBL12607298 0.78 TEAD4 (1.00) TEAD4ALDH1A1MAPTTDP1POLB
SCHEMBL13018332 0.78 TEAD4 (1.00) TEAD4ALDH1A1MAPTTDP1POLB
SCHEMBL177861 0.78 TEAD4 (1.00) TEAD4ALDH1A1MAPTTDP1POLB
SCHEMBL18679847 0.77 NPBWR1 (0.36) TEAD4ALDH1A1MAPTTDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11732134-B2 Benzocyclobutene-containing polyimide resin and its composition, manufacturing method, redistribution layer, polyimide film, and use CHIN YEE CHEMICAL INDUSTRIES CO., LTD. (TW) 2023-08-22 US disclosed
US-20140171588-A1 COMPOSITION FOR FLEXIBLE SUBSTRATE AND FLEXIBLE SUBSTRATE FORMED FROM THE SAME CHI MEI CORPORATION (TW) 2014-06-19 US disclosed