Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | RGS12 | O14924 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17190564 | 0.90 | STAT3 (0.47) | STAT3HIF1ATERTMEN1KMT2A | |
| SCHEMBL17190545 | 0.85 | STAT3 (0.47) | STAT3HIF1ATERTMEN1KMT2A | |
| SCHEMBL21923810 | 0.79 | TERT (0.40) | STAT3HIF1ATERTMEN1KMT2A | |
| SCHEMBL17190565 | 0.79 | STAT3 (0.49) | STAT3HIF1ATERTMEN1KMT2A | |
| SCHEMBL17190544 | 0.78 | STAT3 (0.46) | STAT3HIF1ATERTMEN1KMT2A | |
| SCHEMBL17190577 | 0.76 | STAT3 (0.40) | STAT3HIF1ATERTMEN1KMT2A | |
| SCHEMBL17190557 | 0.75 | STAT3 (0.41) | STAT3HIF1ATERTMEN1KMT2A | |
| SCHEMBL17190558 | 0.73 | STAT3 (0.43) | STAT3HIF1ATERTMEN1KMT2A | |
| SCHEMBL2671337 | 0.73 | STAT3 (0.67) | STAT3HIF1ATERTMEN1KMT2A | |
| SCHEMBL29384023 | 0.73 | STAT3 (0.67) | STAT3HIF1ATERTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014090373-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-06-19 | — | — | WO | disclosed |