Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | RGS12 | O14924 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 7/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17190544 | 0.91 | STAT3 (0.46) | STAT3HIF1ANPC1RAB9AMEN1 | |
| SCHEMBL17190545 | 0.90 | STAT3 (0.47) | STAT3HIF1ANPC1RAB9AMEN1 | |
| SCHEMBL2607401 | 0.86 | STAT3 (0.50) | STAT3HIF1ANPC1RAB9AMEN1 | |
| SCHEMBL17190564 | 0.85 | STAT3 (0.47) | STAT3HIF1ANPC1RAB9AMEN1 | |
| SCHEMBL13196670 | 0.81 | PIN1 (0.40) | STAT3HIF1ANPC1RAB9AMEN1 | |
| SCHEMBL2607403 | 0.80 | STAT3 (0.45) | STAT3HIF1ANPC1RAB9AMEN1 | |
| SCHEMBL13784297 | 0.79 | STAT3 (0.47) | STAT3HIF1ANPC1RAB9AMEN1 | |
| SCHEMBL17190546 | 0.79 | PPARG (0.33) | HTTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17190552 | 0.78 | PPARG (0.33) | HTTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17228818 | 0.78 | PPARG (0.33) | HTTKDM4EALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701905-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-07-11 | — | — | US | disclosed |
| US-20160033807-A1 | DEVICE FOR REGULATING THE PASSAGE OF ENERGY | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | US | disclosed |
| US-20150315473-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| US-20150299577-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |