Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | RGS12 | O14924 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17190545 | 0.92 | STAT3 (0.47) | STAT3HIF1ATERTMEN1RGS12 | |
| SCHEMBL17190577 | 0.91 | STAT3 (0.40) | STAT3HIF1ATERTMEN1RGS12 | |
| SCHEMBL17190564 | 0.87 | STAT3 (0.47) | STAT3HIF1ATERTMEN1RGS12 | |
| SCHEMBL13784298 | 0.84 | STAT3 (0.49) | STAT3HIF1ATERTMEN1RGS12 | |
| SCHEMBL17483878 | 0.83 | PPARG (0.35) | TERTMAPTCDC25A | |
| SCHEMBL2607401 | 0.83 | STAT3 (0.50) | STAT3HIF1ATERTMEN1RGS12 | |
| SCHEMBL17483942 | 0.82 | CDC25A (0.36) | KDM4EALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL8071104 | 0.82 | STAT3 (0.65) | STAT3HIF1ATERTMEN1RGS12 | |
| SCHEMBL418871 | 0.82 | STAT3 (0.65) | STAT3HIF1ATERTMEN1RGS12 | |
| SCHEMBL284967 | 0.82 | STAT3 (0.65) | STAT3HIF1ATERTMEN1RGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043782-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2024-07-23 | — | — | US | disclosed |
| US-11702597-B2 | Azo dye | MERCK PATENT GMBH (DE) | 2023-07-18 | — | — | US | disclosed |
| US-11667845-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2023-06-06 | — | — | US | disclosed |
| US-20180142153-A1 | THIADIAZOLOQUINOXALINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-05-24 | — | — | US | disclosed |
| US-20170267929-A1 | DEVICE FOR REGULATING THE PASSAGE OF ENERGY | MERCK PATENT GMBH (DE) | 2017-09-21 | — | — | US | disclosed |
| US-9701905-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-07-11 | — | — | US | disclosed |
| US-20160319592-A1 | DEVICE FOR REGULATING THE PASSAGE OF LIGHT | MERCK PATENT GMBH (DE) | 2016-11-03 | — | — | US | disclosed |
| US-20160108317-A1 | DEVICE FOR CONTROLLING THE PASSAGE OF ENERGY, CONTAINING A DICHROIC DYE COMPOUND | MERCK PATENT GMBH (DE) | 2016-04-21 | — | — | US | disclosed |
| US-20160033807-A1 | DEVICE FOR REGULATING THE PASSAGE OF ENERGY | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | US | disclosed |
| US-20150315473-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| US-20150299577-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108317-A1 | DEVICE FOR CONTROLLING THE PASSAGE OF ENERGY, CONTAINING A DICHROIC DYE COMPOUND | CRY1, SLC25A1, CRY2 | STAT3 4607/4885HIF1A 2799/4885TERT 253/4885 |
| US-11667845-B2 | Liquid crystalline medium | NEFM, CCNI, MYT1 | STAT3 936/4885HIF1A 2569/4885TERT 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.