SCHEMBL158108

SCHEMBL158108

O=C(c1ccccc1)C1C=CC(O)(O)C=C1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.36
MAPT P10636 2/20 0.36
ALOX15 P16050 1/20 0.36
HBB P68871 1/20 0.36
EPHX1 P07099 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CES2 O00748 3/20 0.33
CES1 P23141 3/20 0.33
ALDH1A1 P00352 3/20 0.33
DAO P14920 1/20 0.33
TSHR P16473 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
MGLL Q99685 1/20 0.33
MCL1 Q07820 1/20 0.33
TRPA1 O75762 1/20 0.32
MAPK1 P28482 1/20 0.32
GSK3B P49841 1/20 0.32
HIF1A Q16665 1/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL424984 0.81 KDM4E (0.39) HTTMAPTALOX15SMN1; SMN2ALDH1A1
SCHEMBL8172322 0.80 TSHR (0.35) HTTMAPTALOX15HBBEPHX1
SCHEMBL7097259 0.80 HTT (0.34) HTTMAPTALOX15HBBEPHX1
SCHEMBL3120601 0.78 TSHR (0.36) HTTMAPTALOX15HBBEPHX1
SCHEMBL344146 0.78 HTT (0.38) HTTMAPTALOX15HBBEPHX1
SCHEMBL9459123 0.78 GSK3B (0.33) HTTMAPTALOX15HBBSMN1; SMN2
SCHEMBL180232 0.76 TSHR (0.34) HTTMAPTALOX15HBBEPHX1
SCHEMBL9732807 0.76 TSHR (0.34) HTTMAPTALOX15HBBEPHX1
SCHEMBL7855173 0.76 TSHR (0.34) HTTMAPTALOX15HBBEPHX1
SCHEMBL10435301 0.75 HTT (0.48) HTTMAPTALOX15HBBEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115806734-A Anti-aging polycarbonate automobile lampshade and preparation process thereof 江苏明朗医疗器械科技有限公司 2023-03-17 CN claimed
EP-1778176-B1 COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES HENKEL AG & CO KGAA (DE) 2012-07-25 EP claimed
US-20020161075-A1 Polymeric articles containing hindered amine light stabilizers based on multi-functional carbonyl compounds CYTEC TECHNOLOGY CORP. 2002-10-31 US claimed
JP-4117461-A None JP disclosed
CN-115806734-A Anti-aging polycarbonate automobile lampshade and preparation process thereof 江苏明朗医疗器械科技有限公司 2023-03-17 CN disclosed
EP-2439070-B1 Infrared-sensitive positive-working image forming material, planographic printing plate precursor, and method for manufacturing a planographic printing plate FUJIFILM CORP (JP) 2019-07-17 EP disclosed
EP-3191587-A1 CELLOBIOHYDROLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME Novozymes A/S (DK) 2017-07-19 EP disclosed
WO-2016040265-A1 CELLOBIOHYDROLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME NOVOZYMES A/S (DK) 2016-03-17 WO disclosed
EP-2964760-A1 CELLOBIOHYDROLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME Novozymes A/S (DK) 2016-01-13 EP disclosed
EP-2931885-A1 POLYPEPTIDES HAVING CELLULOLYTIC ENHANCING ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME Novozymes A/S (DK) 2015-10-21 EP disclosed
EP-2903412-A1 POLYPEPTIDES HAVING CELLULOLYTIC ENHANCING ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME Novozymes A/S (DK) 2015-08-12 EP disclosed
US-20100278767-A1 Lightening Agents and/or Dyes that Contain Aldehyde(s) HENKEL AG & CO. KGAA (DE) 2010-11-04 US disclosed
US-20050214677-A1 Light-sensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. 2005-09-29 US disclosed
US-20050214678-A1 Light-sensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. 2005-09-29 US disclosed
EP-0625547-B1 Flame retardative polycarbonate resin composition IDEMITSU PETROCHEMICAL CO (JP) 1998-10-14 EP disclosed
US-5194456-A For intraocular/contact lenses and eyeglasses with lenses of polycarbonates IOPTEX RESEARCH, INC. (US) 1993-03-16 US disclosed
JP-H04117461-A POLYMER MATERIAL COMPOSITION HAVING IMPROVED LIGHT RESISTANCE ASAHI DENKA KOGYO KK 1992-04-17 JP disclosed
EP-0395049-A1 Positive-working photoresist composition FUJI PHOTO FILM CO., LTD. (JP) 1990-10-31 EP disclosed
EP-0369219-A1 Light-sensitive compounds, preparation of a light-sensitive mixture therewith and a recording material HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-23 EP disclosed
EP-0253548-A2 Method for the determination of occult blood and chemical compositions therefor SAVYON DIAGNOSTICS LTD. (IL) 1988-01-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100278767-A1 Lightening Agents and/or Dyes that Contain Aldehyde(s) CCR3, CBR3, CCRL2 HTT 3438/4885MAPT 3855/4885ALOX15 2839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.